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Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney inter., Suppl. 2012;2: 1-138.

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Article

Dialysis Disequilibrium Syndrome

1Department of Emergency Medicine, McLaren Oakland, Pontiac, USA

2Department of Nephrology, McLaren Oakland, Pontiac, USA


American Journal of Medical Case Reports. 2018, Vol. 6 No. 4, 68-71
DOI: 10.12691/ajmcr-6-4-4
Copyright © 2018 Science and Education Publishing

Cite this paper:
Christina George D.O, Sreelatha Penumalee M.D, David Minter D.O. Dialysis Disequilibrium Syndrome. American Journal of Medical Case Reports. 2018; 6(4):68-71. doi: 10.12691/ajmcr-6-4-4.

Correspondence to: Christina  George D.O, Department of Emergency Medicine, McLaren Oakland, Pontiac, USA. Email: christina.lis710@gmail.com

Abstract

Dialysis disequilibrium syndrome (DDS) is a rare complication of dialysis leading to neurological symptoms which can vary in severity from a simple headache to coma and death. The debate continues on the specific causes of DDS and centers around two main theories; the reverse urea effect and cerebral acidosis. It can be a challenge to predict in which patients DDS will occur, and an even more difficult syndrome to treat while the best known treatment is prevention. A case where DDS led to irreversible brain damage despite preventative measures in place will be discussed along with a discussion of current literature surrounding dialysis disequilibrium syndrome (DDS) and its treatment.

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