1Molecular Pathology Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
2Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
3Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
American Journal of Cancer Prevention.
2018,
Vol. 6 No. 2, 24-28
DOI: 10.12691/ajcp-6-2-2
Copyright © 2018 Science and Education PublishingCite this paper: Mazaher Ramezani, Kaivan Mohammadi, Masoud Sadeghi. Follicular Carcinoma of Thyroid with the First Presentation as Vertebral Column Metastasis: A Case-report.
American Journal of Cancer Prevention. 2018; 6(2):24-28. doi: 10.12691/ajcp-6-2-2.
Correspondence to: Masoud Sadeghi, Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Email:
Sadeghi_mbrc@yahoo.comAbstract
Follicular carcinoma of thyroid is the second most common type of thyroid cancer that its incidence has increased in recent years. Herein, the study reported a 64-year male case of follicular carcinoma of thyroid that his first presentation was vertebral column metastasis. His chief complaint was back pain. In the past medical history, the patient had hypothyroidism and was opium inhalation addict since 15 years ago. Thoraco-lumbar magnetic resonance imaging (MRI) demonstrated spinal tumor of T10. The pathology report showed metastatic follicular carcinoma of thyroid with Thyroid transcription factor-1 (TTF-1), Thyroglobulin (TG), and Cytokeratin-7 (CK-7) positivity. Then thyroidectomy confirmed the diagnosis. In conclusion, follicular carcinoma of thyroid may be presented with spinal column metastasis. Pathologist should consider this diagnosis in the differential diagnosis of metastatic carcinoma in vertebral column and use Thyroglobulin with TTF-1 in immunohistochemistry panel for definite diagnosis and identification of origin.
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