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Klion AD. How I treat hypereosinophilic syndromes. Blood. 2015; 126(9): 1069-77.

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Article

Dermatologic Manifestations and Pulmonary Involvement in Two Patients with Hypereosinophilic Syndrome - A Case Series

1Department of Hematology and Medical Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Department of Hematology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3Department of Genetics, Shahid Sadoughi University of Medical Science, Yazd, Iran

4Department of Nursing, Kermanshah University of Medical Sciences, Kermanshah, Iran


American Journal of Cancer Prevention. 2018, Vol. 6 No. 2, 20-23
DOI: 10.12691/ajcp-6-2-1
Copyright © 2018 Science and Education Publishing

Cite this paper:
Mehrdad Payandeh, Afshin Karami, Noorodin Karami, Mehrnoosh Aeinfar, Fatemeh Feizi, Amir Yami, Akram Sourni, Hedieh Heidary. Dermatologic Manifestations and Pulmonary Involvement in Two Patients with Hypereosinophilic Syndrome - A Case Series. American Journal of Cancer Prevention. 2018; 6(2):20-23. doi: 10.12691/ajcp-6-2-1.

Correspondence to: Afshin  Karami, Department of Hematology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Email: afshinkarami72@gmail.com

Abstract

Hypereosinophilic syndrome is a group of disorders described by excessive production of eosinophils, their infiltration and the release of mediators that cause damage to multiple organs. Two patients of 67 and 38 years old, were referred to the clinic of Hematology and Oncology, Kermanshah, Iran, in 2016 and 2017, respectively. In the first case, there was no suspicious item in the patient's medical records and his most prominent features were pulmonary emphysema, and hypopigmented lesions, while in the second case, in addition to having a history of asthma, lesions of eczema were also seen. Hence, according to these characteristics and the results of the tests performed, our differential diagnosis was the Hypereosinophilic syndrome. We started the treatment with two types of drugs, Imatinib and Prednisolone. The treatment of patients is still ongoing and their condition was relatively promising.

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