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Article

Assay of Hydroxypropoxy Group in Hydroxypropyl Cellulose by United States Pharmacopeia-Titration Method

1Complete Analysis Laboratories, Analytical Chemistry Research Department, 810 North 2nd Ave, Highland Park, NJ. 08904-USA

2Eutech Scientific Services, Analytical Chemistry Research Department, 810 North 2nd Ave, Highland Park, NJ. 08904-USA


World Journal of Analytical Chemistry. 2018, Vol. 6 No. 1, 1-3
DOI: 10.12691/wjac-6-1-1
Copyright © 2018 Science and Education Publishing

Cite this paper:
Y. Yildiz, M. Dasguptha. Assay of Hydroxypropoxy Group in Hydroxypropyl Cellulose by United States Pharmacopeia-Titration Method. World Journal of Analytical Chemistry. 2018; 6(1):1-3. doi: 10.12691/wjac-6-1-1.

Correspondence to: Y.  Yildiz, Complete Analysis Laboratories, Analytical Chemistry Research Department, 810 North 2nd Ave, Highland Park, NJ. 08904-USA. Email: sayatoglu@yahoo.com

Abstract

Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water soluble and organic solubility, used as food additive and sieving matrix for DNA separation. Hydroxypropyl Cellulose is partially substituted poly (hydroxypropyl) ether of cellulose. It contains NLT 53.4% and NMT 80.5% of hydroxypropoxy groups, calculated on the dried basis. It may contain ether suitable anticaking agents, and 0.6 percent of silica (SiO2). The average sample result has been determined 67.3% which was conforms to USP/NF specifications for Hydroxypropyl cellulose.

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