1Nephrology and Dialysis, Civic and Di Cristina Hospital, Palermo, Italy
2Anatomic Pathology, Civic and Di Cristina Hospital, Palermo, Italy
American Journal of Medical Sciences and Medicine.
2013,
Vol. 1 No. 1, 1-4
DOI: 10.12691/ajmsm-1-1-1
Copyright © 2013 Science and Education PublishingCite this paper: Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo. Clinical and Histological Features in Wegener Granulomatosis.
American Journal of Medical Sciences and Medicine. 2013; 1(1):1-4. doi: 10.12691/ajmsm-1-1-1.
Correspondence to: Li Cavoli Gioacchino, Nephrology and Dialysis, Civic and Di Cristina Hospital, Palermo, Italy. Email:
Abstract
Wegener Granulomatosis is a systemic ANCA-associated Vasculitis, affecting small-to-medium vessels. Clinical presentation with simultaneous involvement of kidney and upper and lower respiratory tract is unusual. There are few histological reports regarding lung biopsy in WG because clinical and radiologic features are diagnostic. Sometimes radiologic findings can be unusual. We detected an instructive case of WG, analyzing clinical course, laboratory and radiological features, kidney, lung and larynx histological pictures. Besides renal biopsy, nephrology team performed larynx and lung biopsies because of unusual clinical presentation, computed tomography chest examination and relevant malignancy risk regarding following immunosuppressant therapy. WG is a point of interest for clinical multidisciplinary activity. Diagnosis of WG is a combination of clinical, laboratory and pathologic features. Collaboration between different specialities help to improve current diagnostic activity.
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