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Ramaraj R, Movahed MR. Reverse or inverted takotsubo cardiomyopathy (reverse left ventricular apical ballooning syndrome) presents at a younger age compared with the mid or apical variant and is always associated with triggering stress. Congest Heart Fail.16 (6). 284-286. November 2010.

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Article

Reverse Takotsubo Cardiomyopathy, Flash Pulmonary Edema and Cardiac Arrest after Topical Nasal Phenylephrine and Mucosal Epinephrine Injection

1Department of Anesthesiology, Thomas Jefferson University Hospitals, Philadelphia, 19107, PA, USA


American Journal of Medical Case Reports. 2017, Vol. 5 No. 12, 293-297
DOI: 10.12691/ajmcr-5-12-3
Copyright © 2018 Science and Education Publishing

Cite this paper:
Uzung Yoon, Elia Elia. Reverse Takotsubo Cardiomyopathy, Flash Pulmonary Edema and Cardiac Arrest after Topical Nasal Phenylephrine and Mucosal Epinephrine Injection. American Journal of Medical Case Reports. 2017; 5(12):293-297. doi: 10.12691/ajmcr-5-12-3.

Correspondence to: Uzung  Yoon, Department of Anesthesiology, Thomas Jefferson University Hospitals, Philadelphia, 19107, PA, USA. Email: uzyoon@gmail.com

Abstract

Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy, is characterized by acute reversible apical ventricular dysfunction and apical akinesis in the absence of obstructive coronary artery disease. Reverse-takotsubo is a variant form of takotsubo cardiomyopathy with basal and midventricular dysfunction and normal apical function. It is known to be more common in young patients. We present a case of a 14-year-old patient who developed reverse-takotsubo cardiomyopathy with flash pulmonary edema after topical nasal phenylephrine and iatrogenic epinephrine containing local anesthetic injection for a dental procedure. Patient experienced cardiac arrest but was resuscitated successfully and transferred to the cardiac intensive care unit. Postoperative echocardiogrpahy showed normal coronary arteries and mild left ventricular hypertrophy with uncertain correlation for the cardiac event, and the patient was discharged home with no complications.

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