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Sundar, S., Chakravarty, J., Agarwal, D., Rai, M., and Murray, H.W., “Single-Dose liposomal Amphotericin B for visceral leishmaniasis in India,” N Engl J Med, 362. 504-512. Feb.2010.

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Article

A Case of African Visceral Leishmaniasis (VL) Treated with a Combination of Liposomal Amphotericin-B and oral Miltefosine

1Internal Medicine, Indraprastha Apollo Hospitals, New Delhi, India

2Biocon Ltd., Bangalore, India


American Journal of Medical Case Reports. 2017, Vol. 5 No. 5, 126-128
DOI: 10.12691/ajmcr-5-5-6
Copyright © 2017 Science and Education Publishing

Cite this paper:
Alok Agarwal, Makardhwaj Sarvadaman Shrivastava, Amit Kumar Vishwakarma. A Case of African Visceral Leishmaniasis (VL) Treated with a Combination of Liposomal Amphotericin-B and oral Miltefosine. American Journal of Medical Case Reports. 2017; 5(5):126-128. doi: 10.12691/ajmcr-5-5-6.

Correspondence to: Alok  Agarwal, Internal Medicine, Indraprastha Apollo Hospitals, New Delhi, India. Email: alok_doc2003@hotmail.com

Abstract

A 36-year-old Nigerian man was assessed for chronic recurrent fever, generalized weakness, body aches, epistaxis and bleeding gums of 3-month duration. Despite receiving treatment for suspected malaria twice and undergoing multiple courses of antibiotics for suspected infections, his symptoms persisted. Examination revealed hepatosplenomegaly, lymphadenopathy, and severe pallor. Investigations revealed severe anemia, pancytopenia, raised globulin levels. Bone marrow biopsy revealed Leishmania Donovani (LD) bodies. He received treatment with a short duration of high-dose liposomal Amphotericin B followed by outpatient oral Miltefosine to which he responded successfully.

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