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Agoff SN, Lawton TJ. Papillary Lesions of the Breast With and Without Atypical Ductal Hyperplasia: Can We Accurately Predict Benign Behavior From Core Needle Biopsy? Am J Clin Pathol.2004;122(3):440-3.

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Article

Invasive Papillary Carcinoma of the Breast Presenting after Metastatic Mucinous Adenocarcinoma: Report of a Rare Case

1Molecular Pathology Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

3Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran


American Journal of Medical Sciences and Medicine. 2017, Vol. 5 No. 1, 20-22
DOI: 10.12691/ajmsm-5-1-3
Copyright © 2017 Science and Education Publishing

Cite this paper:
Mazaher Ramezani, Farhad Kavousi, Setareh Afzali, Masoud Sadeghi. Invasive Papillary Carcinoma of the Breast Presenting after Metastatic Mucinous Adenocarcinoma: Report of a Rare Case. American Journal of Medical Sciences and Medicine. 2017; 5(1):20-22. doi: 10.12691/ajmsm-5-1-3.

Correspondence to: Masoud  Sadeghi, Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Email: Sadeghi_mbrc@yahoo.com

Abstract

Breast cancer constitutes a heterogenous group of lesions. Invasive papillary carcinoma of the breast is a rare form of breast cancer with less aggressive behavior which may have mucinous differentiation. Histologically papillary projections with fibrovascular core and epithelial proliferation are present. Signet ring morphology and extracellular mucin production can be seen but myoepithelial cells are absent. We reported a case of invasive papillary carcinoma of the breast in a 74-year-old lady without mucin production, which first presentation was a metastasis of unknown origin to the spinal column as adenocarcinoma with mucin production. In conclusion, although invasive papillary carcinoma of the breast is known as a less aggressive tumor, but its presentation may be with metastasis and mucin production, despite of non-mucinous primary tumor.

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