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Heddle N M, Wentworth P, Anderson D R, Emmerson D, Kelton J G, Blajchman M A. Three examples of Rh haemolytic disease of the newborn with a negative direct antiglobulin test. Transfusion Medicine. 1995; 5 113-11.

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Article

Inappropriate Blood Transfusion in Neonatal Hemolytic Anemia Due to Anti-c

1MVZ Dr. Eberhard & Partner, Dortmund, Germany

2Zentrum für Labormedizin und Mikrobiologie, Essen, Germany


American Journal of Medical Case Reports. 2017, Vol. 5 No. 3, 56-58
DOI: 10.12691/ajmcr-5-3-3
Copyright © 2017 Science and Education Publishing

Cite this paper:
Falko Strotmann, Corinna Nöcker, Nicole Crummenerl, Bianca Karnuth, Nilma Kamp, Gerd Hafner. Inappropriate Blood Transfusion in Neonatal Hemolytic Anemia Due to Anti-c. American Journal of Medical Case Reports. 2017; 5(3):56-58. doi: 10.12691/ajmcr-5-3-3.

Correspondence to: Falko  Strotmann, MVZ Dr. Eberhard & Partner, Dortmund, Germany. Email: strotmann@labmed.de

Abstract

For transfusion in premature infants and newborns red blood cell (RBC) units of blood group 0, D–, and haplotype ccddee are often falsely regarded as universal compatible since they are suitable for all AB0 constellations between mother and child. In case of maternal diaplacental immunization with antibodies directed against RBC surface antigen Rhc (rare) or Rhe (very rare) these concentrates should be retained due to the risk of hemolytic disease. We report a case of immune mediated hemolytic anemia of a newborn due to antic and antiE where this restriction was not considered.

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