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Aguayo-Patrón S, Beltrán-Sauceda L, Calderón de la Barca AM. A population-wide applicable HLA-DQ2 and DQ8 genotyping using DNA from dried blood spots and duplex allele-specific qPCR amplification. Scandinavian Journal of Clinical and Laboratory Investigation. 2016 Oct 2; 76(7): 581-7.

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Article

Screening for Celiac Disease in Rheumatology: HLA First?

1Pediatrics Department, Setif University Hospital; Setif-1 University, Algeria

2Biochemistry Department, Setif University Hospital; Setif-1 University, Algeria


International Journal of Celiac Disease. 2017, Vol. 5 No. 1, 30-32
DOI: 10.12691/ijcd-5-1-2
Copyright © 2017 Science and Education Publishing

Cite this paper:
Hakim Rahmoune, Nada Boutrid, Mounira Amrane, Belkacem Bioud. Screening for Celiac Disease in Rheumatology: HLA First?. International Journal of Celiac Disease. 2017; 5(1):30-32. doi: 10.12691/ijcd-5-1-2.

Correspondence to: Hakim  Rahmoune, Pediatrics Department, Setif University Hospital; Setif-1 University, Algeria. Email: rahmounehakim@gmail.com

Abstract

HLA genes have been shown to be strongly associated with a large repertoir of autoimmune diseases including Rheumatoid Arthritis (RA), Juvenile idiopathic arthritis (JIA) and Celiac Disease (CD). The present article will discuss what is the place of performing celiac disease associated serology in face of a rheumatologic patient, when gluten enteropaty is suspected. More specifically, should HLA be done prior to the serology? Unnecessary serial serological CD screening in such rheumatology patients could be avoided by performing an HLA typing, as a long-life marker of genetically CD-susceptible patients.

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