The review summarizes literature dealing with the synthesis of thiazolidinoneand β-lactamVarious methods for synthesis of thiazolidinone and β-lactamare discussed. Like boiling benzene thioglycolic acid was added to (1)a-d using a water separator to give thiazolidinone derivatives (2)a-d. Also Reaction of the Schiff bases of 3 and /or5 with one mole of thioglycolic acid was proceeded smoothly to afford the corresponding thiazolidinone derivatives 6,7 respectively. The synthesis of a new type of compound, 2-hydrazolyl-5,5-diphenyl-4-thiazolidinone (24), obtained by treatment of thiosemicarbazone with benzyl in basic media. β-lactams were prepared by N-Tosyl-3-halo-3-butenylamines underwent efficient Ullmann-type coupling to afford 2-alkylideneazetidines, which could be readily converted to the corresponding β-lactams by oxidation with O₃ to give β-lactams 119. A chiral N-heterocyclic carbene catalyzed the Staudinger reaction of arylalkylketenes with a variety of N-tert-butoxycarbonylarylimines to give the corresponding cis-β-lactams 124.

thiazolidinone, β-lactam, thioglycolic acid, Schiffs bases, synthesis, condensation