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Sountoulides P, Giovis G, Metaxa L, Panagopoulos V, Kikidakis D, Filintatzi C, Paschalidis K. Sarcomatoid RCC, a Highly Aggressive Subtype of Renal Cell Carcinoma. Global Journal of Pathology and Microbiology. 2013.

has been cited by the following article:


Rapidly Metastasizing Sarcomatoid Renal Cell Carcinoma in a 76-year Old Male

1Univerity of Missouri, United States

American Journal of Medical Case Reports. 2016, Vol. 4 No. 6, 221-223
DOI: 10.12691/ajmcr-4-6-10
Copyright © 2016 Science and Education Publishing

Cite this paper:
Nathaniel Moulton, Joe Devasahayam, Rohini Kannuswamy, Arul Chandran, Hunter Hofmann. Rapidly Metastasizing Sarcomatoid Renal Cell Carcinoma in a 76-year Old Male. American Journal of Medical Case Reports. 2016; 4(6):221-223. doi: 10.12691/ajmcr-4-6-10.

Correspondence to: Joe  Devasahayam, Univerity of Missouri, United States. Email:


Renal Cell Carcinoma (RCC), the most lethal urological cancer has many variants. A relatively uncommon variant, sarcomatoid RCC (sRCC) is one of the most aggressive morphotypes of RCC. The complexity of this tumor is mainly due to the difficulty in its diagnosis as it can present with relatively subtle symptoms and quickly progress to very advanced stage with unusually rapid metastasis and could be fatal. We present a male patient with this rare tumor who initially presented with vague multi-system complaints. The patient rapidly deteriorated and expired following aggressive therapy and was subsequently found to have metastatic sRCC upon autopsy. We review the characteristic features of sRCC and analyze the clinical presentations, histology, prognosis as well as the atypical presentations of sRCC. This case therefore, highlights the difficulty of diagnosis prior to nephrectomy and reinforces the need for a high degree of suspicion for renal malignancies especially in the older patient.