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Reid S, Renwick A, Seal S, et al. Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms’ tumour. J Med Genet 2005; 42 (2): 147-51.

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Article

Wilms’ Tumor of the Kidney: Insights into Risk Factors, Pathogenesis, Diagnosis and Management

1Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, KSA

2Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt

3Final year student, College of Pharmacy, Taif University, Taif, KSA


Journal of Cancer Research and Treatment. 2016, Vol. 4 No. 3, 52-54
DOI: 10.12691/jcrt-4-3-4
Copyright © 2016 Science and Education Publishing

Cite this paper:
Ahmed M. Kabel, Manal Alosaimy, Walaa Aljeaid, Bayan Alhumaiany, Nada Albardi. Wilms’ Tumor of the Kidney: Insights into Risk Factors, Pathogenesis, Diagnosis and Management. Journal of Cancer Research and Treatment. 2016; 4(3):52-54. doi: 10.12691/jcrt-4-3-4.

Correspondence to: Ahmed  M. Kabel, Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, KSA. Email: drakabel@gmail.com

Abstract

Wilms’ tumor is a rare disease of the kidney that usually affects newborn and young children. It is the commonest renal tumor of childhood affecting one in 10,000 children. It may spread into the other kidney if it has not been discovered early. Diagnosis depends on physical examination and radiographic images while the treatment decision is taken after determining the stage of the disease according to the occurrence of metastasis or the presence of the cancer cells in both kidneys. Lines of treatment include surgical excision, high dose chemotherapy and radiotherapy. Prognosis depends on the stage of the disease at diagnosis, tumor size, histopathological features of the tumor and the age of the patient.

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