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Husby, S., et al., European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr. 54(1): p. 136-60.

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Article

Nonspecific Symptoms in Celiac Disease- Case Report

1Mother and Child Department, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania

2Third Pediatric Clinic, Emergency Clinical Hospital for Children, Cluj-Napoca, Romania


International Journal of Celiac Disease. 2016, Vol. 4 No. 2, 71-73
DOI: 10.12691/ijcd-4-2-9
Copyright © 2016 Science and Education Publishing

Cite this paper:
Valentina Sas, Camelia I. Bud, Ioana Fodor, Sorin C. Man. Nonspecific Symptoms in Celiac Disease- Case Report. International Journal of Celiac Disease. 2016; 4(2):71-73. doi: 10.12691/ijcd-4-2-9.

Correspondence to: Camelia  I. Bud, Third Pediatric Clinic, Emergency Clinical Hospital for Children, Cluj-Napoca, Romania. Email: cami_bud01pd@yahoo.com

Abstract

Celiac disease is an immune-mediated systemic disorder with a genetic predisposition. The availability of more specific serology tests showed that celiac disease is more common than previously suspected and that many patients do not demonstrate specific clinical or even histological sings. We present a case of celiac disease with the unset at 5 years, with recurrent episodes of diarrhea, weight loss and anemia. The serology tests showed a high level of IgA tissue transglutaminase antibodies, exceeding 10 times the upper limit but the intestinal biopsy showed normal size villi, intact surface epithelium and a lymphoplasmacytic infiltrate at chorionic level (Marsh 1). The diagnosis of celiac disease was confirmed by resolution of symptoms and normal tissue transglutaminase antibodies level, six month after starting the gluten free diet.

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