1Department of Immunology and Allergology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
2Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
3Emergency Hospital for Children, Cluj-Napoca, Romania
4Institute for Interdisciplinary Research in Bio-Nano-Science, “Babes-Bolyai” University, Cluj-Napoca, Romania
International Journal of Celiac Disease.
2016,
Vol. 4 No. 2, 61-63
DOI: 10.12691/ijcd-4-2-10
Copyright © 2016 Science and Education PublishingCite this paper: Gabriel Samasca, Pirvan Alexandru, Genel Sur, Abrudan Carmen, Iulia Lupan, Diana Deleanu. IgA Tissue Transglutaminase Antibodies at Different cut-offs in the Evaluation of Possible Celiac Patients.
International Journal of Celiac Disease. 2016; 4(2):61-63. doi: 10.12691/ijcd-4-2-10.
Correspondence to: Iulia Lupan, Institute for Interdisciplinary Research in Bio-Nano-Science, “Babes-Bolyai” University, Cluj-Napoca, Romania. Email:
iulia.lupan@gmail.comAbstract
The celiac disease screening with IgA tissue transglutaminase antibodies depends on the cut-off reaction, therefore many patients with values less but close to the cut-off may be undiagnosed. Material and Method. We conducted the CD screening with IgA tissue transglutaminase antibodies in a group of 1616 children during 2014 at a cut-off of 25 U/ml and at a cut-off of 10 U/ml. We also wanted to compare our results with IgA tissue transglutaminase antibodies prevalence from other countries. Results. We found a IgA tissue transglutaminase antibodies prevalence rate of 3% for values higher 25 U/ml and a IgA tissue transglutaminase antibodies prevalence rate of 1.6% for values between 10-25 U/ml. A prevalence of 13.6% for IgA tissue transglutaminase antibodies was observed in , and . Conclusions. We observed a 4.6% IgA tissue transglutaminase antibodies prevalence at a cut-off of 10 U/ml. Prevalence of IgA tissue transglutaminase antibodies from Romania is lowered compared with other European countries.
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