Article citationsMore >>

Taguchi, K., Scha¨fers, R.F., Michel, M.C., “Radioreceptor assay analysis of tamsulosin and terazosin pharmacokinetics.” Br J Clin Pharmacol, 1998, 45, 49-55.

has been cited by the following article:

Article

Spectrophotometry Method for the Determination of Terazosin in Tablet Formulation

1Department of Pharmaceutics, Institute of Biomedical Education and Research, Mangalayatan University, Beswan, Aligarh, India

2B.R. Nahata College of Pharmacy, Mhow-Neemuch Road, Mandsaur (M.P), India


World Journal of Analytical Chemistry. 2016, Vol. 4 No. 1, 11-16
DOI: 10.12691/wjac-4-1-3
Copyright © 2016 Science and Education Publishing

Cite this paper:
Alankar Shrivastava, Lalita Dhakad. Spectrophotometry Method for the Determination of Terazosin in Tablet Formulation. World Journal of Analytical Chemistry. 2016; 4(1):11-16. doi: 10.12691/wjac-4-1-3.

Correspondence to: Alankar  Shrivastava, Department of Pharmaceutics, Institute of Biomedical Education and Research, Mangalayatan University, Beswan, Aligarh, India. Email: alankar.shrivastava@mangalayatan.edu.in

Abstract

Terazosin (TRZ) is indicated in the symptomatic relief of benign prostatic hyperplasia. The presented study is spectrophotometry method for the determination of terazosin in tablet dosage forms. Bromophenol blue was used for ion pair complex with the drug in 1:1 ratio. The linear range, limit of detection (LOD) and limit of quantitation (LOQ) were found to be 1-10, 0.001 and 0.012 μg/ml respectively. The method was found to be specific when applied with some excipients and accurate enough to be applied in tablet formulation.

Keywords