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Rahimzadeh P, Imani F, Faiz SHR, Nikoubakht N, Sayarifard A. Effect of Intravenous Methylprednisolone on Pain after Intertrochanteric Femoral Fracture Surgery. J Clin Diagn Res. 2014;8(4): GC01-GC04.

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Preoperative Intravenous Methylprednisolone to Reduce Postoperative Pain: VAS Assessment

1School of Medicine, Padjadjaran University, Bandung, Indonesia

Global Journal of Surgery. 2016, Vol. 4 No. 1, 5-8
DOI: 10.12691/js-4-1-2
Copyright © 2016 Science and Education Publishing

Cite this paper:
Suwarman, Hendro Sudjono Yuwono. Preoperative Intravenous Methylprednisolone to Reduce Postoperative Pain: VAS Assessment. Global Journal of Surgery. 2016; 4(1):5-8. doi: 10.12691/js-4-1-2.

Correspondence to: Hendro  Sudjono Yuwono, School of Medicine, Padjadjaran University, Bandung, Indonesia. Email:


This study examines the results of VAS score of the effect of preoperative intravenous methylprednisolone to reduce postoperative pain. This clinical trial was a double blind randomized controlled trial, using patients undergoing open cholecystectomy surgery in general anesthesia. The level of pain was assessed using VAS pain scoring by asking how much pain experienced during the first hour of surgery, 2nd, 4th, 8th, 12th and 24th consecutively. Methylprednisolone 125 mg was injected intravenously at 60 minutes preoperatively and 30 minutes before completing the skin sutures. Group I: methylprednisolone given postoperatively; Group II: methylprednisolone given before surgery; Group III: as a Control Group, with each Group number of sample was 10 patients with inclusion criteria: ASA clinical classification I-II, age 20-60 years. Results showed that the treatment produces significantly on VAS levels (p = 0.0000) in every hour, except in the 24th hour (p=0.4999) all Groups resulted the same VAS levels of three. Conclusion: the VAS score of open cholecystectomy given preoperative intravenous methylprednisolone is lower postoperatively than in patients given methylprednisolone at the end of the operation.