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Kurman RJ, Carcangui ML, Harrington, CS, Young RH eds. Tumors of the uterine corpus. WHO Classification of Tumors of Female Reproductive Organs. 4th edn. IARC, Lyon 2014; p 18-139.

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Article

Primary Signet-ring Cell Carcinoma of the Uterine Corpus: A Case Report and Review of the Literature

1Department of Pathology, Women & Infants Hospital/Alpert Medical School of Brown University, Providence, RI 02905


American Journal of Medical Case Reports. 2016, Vol. 4 No. 2, 51-54
DOI: 10.12691/ajmcr-4-2-5
Copyright © 2016 Science and Education Publishing

Cite this paper:
Shivali P. Marketkar, Taslima Hossain, W. Dwayne Lawrence, M. Ruhul Quddus. Primary Signet-ring Cell Carcinoma of the Uterine Corpus: A Case Report and Review of the Literature. American Journal of Medical Case Reports. 2016; 4(2):51-54. doi: 10.12691/ajmcr-4-2-5.

Correspondence to: M.  Ruhul Quddus, Department of Pathology, Women & Infants Hospital/Alpert Medical School of Brown University, Providence, RI 02905. Email: mquddus@wihri.org

Abstract

Pure signet-ring cell carcinomas of the uterine corpus usually raise the suspicion for a metastatic tumor from other primary sites, e.g., breast or the gastrointestinal tract. And if primary in the uterus, it is more commonly of uterine cervical origin with secondary involvement of the corpus. In general, pure mucinous carcinoma of the endometrium is rare and pure signet-ring cell carcinoma, a form of mucinous carcinoma, is even rarer. Only sparse case reports of primary mucinous adenocarcinoma of the uterine corpus with signet-ring cell features have been described in literature. We report here a case of pure mucinous signet-ring cell carcinoma of the uterine corpus in a 63 year-old morbidly obese woman.

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