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Lonardi S, Villanacci V, Lorenzi L, Lanzini A, Lanzarotto F, Carabellese N, et al. Anti-TCR gamma antibody in celiac disease: the value of count on formalin-fixed paraffin-embedded biopsies. Virchows Arch. 2013;463:409-413.

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Article

Counting Intraepithelial Lymphocytes. Immunohistochemistry and Flow Cytometer are Necessary New Steps in the Diagnosis of Celiac Disease

1Department of Microbiology & Infection Control, Laboratory of Immunogenetics, VU University Medical Center, HZ Amsterdam, The Netherlands


International Journal of Celiac Disease. 2016, Vol. 4 No. 1, 7-8
DOI: 10.12691/ijcd-4-1-2
Copyright © 2016 Science and Education Publishing

Cite this paper:
Amado Salvador Peña. Counting Intraepithelial Lymphocytes. Immunohistochemistry and Flow Cytometer are Necessary New Steps in the Diagnosis of Celiac Disease. International Journal of Celiac Disease. 2016; 4(1):7-8. doi: 10.12691/ijcd-4-1-2.

Correspondence to: Amado  Salvador Peña, Department of Microbiology & Infection Control, Laboratory of Immunogenetics, VU University Medical Center, HZ Amsterdam, The Netherlands. Email: pena.as@gmail.com

Abstract

The simple quantitation of intraepithelial lymphocytes per 100 epithelial cells in small bowel has been a valuable addition to the study of the histopathology of celiac disease. However new technology is necessary to increase the accuracy and significance of the subtypes of intraepithelial lymphocytes in the differential diagnosis and the evaluation of gluten related disorders.

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