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Guz-Mark A, Zevit N, Morgenstern S, Shamir R. Duodenal intraepithelial lymphocytosis is common in children without coeliac disease, and is not meaningfully influenced by Helicobacter pylori infection. Aliment Pharmacol Ther. 2014;39:1314-1320.

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Article

Is HLA Typing a Diagnostic Tool in Celiac Disease?

1Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

2Department of Pathology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

3Department of Biophysics, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

4Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

5Department of Molecular Biology, Babes-Bolyai University, Cluj-Napoca, Romania


International Journal of Celiac Disease. 2016, Vol. 4 No. 1, 9-10
DOI: 10.12691/ijcd-4-1-10
Copyright © 2016 Science and Education Publishing

Cite this paper:
Andreea L. Rachisan, Alexandru Pirvan, Nicolae Miu, Dan Gheban, Adrian Hrusca, Gabriel Samasca, Iulia Lupan. Is HLA Typing a Diagnostic Tool in Celiac Disease?. International Journal of Celiac Disease. 2016; 4(1):9-10. doi: 10.12691/ijcd-4-1-10.

Correspondence to: Andreea  L. Rachisan, Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: andreea_rachisan@yahoo.com

Abstract

The “four out of five rule” has not been officially endorsed by official guidelines. However, HLA-associated genes that predispose to CD are found in as much as 30–40% of healthy people. Thus, their presence seems too indecisive for the occurrence of CD.

Keywords