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De Andrés A, Camarero C, Roy G. Distal duodenum versus duodenal bulb: intraepithelial lymphocytes have something to say in celiac disease diagnosis. Dig Dis Sci. 2015;60:1004-1009.

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Article

Is HLA Typing a Diagnostic Tool in Celiac Disease?

1Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

2Department of Pathology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

3Department of Biophysics, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

4Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

5Department of Molecular Biology, Babes-Bolyai University, Cluj-Napoca, Romania


International Journal of Celiac Disease. 2016, Vol. 4 No. 1, 9-10
DOI: 10.12691/ijcd-4-1-10
Copyright © 2016 Science and Education Publishing

Cite this paper:
Andreea L. Rachisan, Alexandru Pirvan, Nicolae Miu, Dan Gheban, Adrian Hrusca, Gabriel Samasca, Iulia Lupan. Is HLA Typing a Diagnostic Tool in Celiac Disease?. International Journal of Celiac Disease. 2016; 4(1):9-10. doi: 10.12691/ijcd-4-1-10.

Correspondence to: Andreea  L. Rachisan, Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: andreea_rachisan@yahoo.com

Abstract

The “four out of five rule” has not been officially endorsed by official guidelines. However, HLA-associated genes that predispose to CD are found in as much as 30–40% of healthy people. Thus, their presence seems too indecisive for the occurrence of CD.

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