Article citationsMore >>

Shab AJ, Karadi RV and PP Parekh (2010)-Isolation, optimization and Production of L-Asparaginase from Coliform bacteria. Asian Journal of Biotechnology; 2: 169-177.

has been cited by the following article:

Article

Isolation and Screening of Marine Bacteria Producing Anti-Cancer Enzyme L-Asparaginase

1Department of Applied Microbiology, Sri Padmavati Mahila Visvavidyalayam, Tirupati


American Journal of Marine Science. 2016, Vol. 4 No. 1, 1-3
DOI: 10.12691/marine-4-1-1
Copyright © 2016 Science and Education Publishing

Cite this paper:
M. Bhargavi, R. Jayamadhuri. Isolation and Screening of Marine Bacteria Producing Anti-Cancer Enzyme L-Asparaginase. American Journal of Marine Science. 2016; 4(1):1-3. doi: 10.12691/marine-4-1-1.

Correspondence to: M.  Bhargavi, Department of Applied Microbiology, Sri Padmavati Mahila Visvavidyalayam, Tirupati. Email: vkrbhargavi@gmail.com

Abstract

PURPOSE: The objective of this investigation was to isolation and screening of marine bacteria for L-asparaginase activity. METHODS: Marine bacteria were isolated from water samples obtained from Kerala sea coast in India. The isolates were identified as marine bacteria by microscopical and bio-chemical tests. Production of L-asparaginase was carried out in submerged fermentation media (glycerol asparagine media). RESULTS: Among three marine isolates subjected to screening only one isolate BKJM-VB showed potential L-asparaginase activity. CONCLUSION: The study revealed that marine bacteria may be a potential source of high yield, high substrate specificity L-asparaginase which is an anti-leukemic agent.

Keywords