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MADERUELO, C., ZARZUELO, A. & LANAO, J. M. 2011. Critical factors in the release of drugs from sustained release hydrophilic matrices. Journal of Controlled Release, 154, 2-19.

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Article

Hydrophilic Matrices for Oral Control Drug Delivery

1Department of Pharmacy, University of Huddersfield, Queensgate, Huddersfield, UK, HD1 3DH


American Journal of Pharmacological Sciences. 2015, Vol. 3 No. 5, 103-109
DOI: 10.12691/ajps-3-5-1
Copyright © 2015 Science and Education Publishing

Cite this paper:
Muhammad U. Ghori, Barbara R Conway. Hydrophilic Matrices for Oral Control Drug Delivery. American Journal of Pharmacological Sciences. 2015; 3(5):103-109. doi: 10.12691/ajps-3-5-1.

Correspondence to: Barbara  R Conway, Department of Pharmacy, University of Huddersfield, Queensgate, Huddersfield, UK, HD1 3DH. Email: b.r.conway@hud.ac.uk

Abstract

Oral controlled drug delivery has gathered tremendous attention over the years due to its many advantages over conventional dosage forms. Polymer-based matrices have become an integral part of the pharmaceutical industry. Hydrophilic matrices are capable of controlling the release of drug over an extended period of time. Hydrophilic polymers, especially the hydrophilic derivatives of cellulose ethers, are frequently used for these applications. Therefore, the objective of this review is to discuss the scientific and physicochemical aspects of these polymeric systems that can affect the drug release from such formulations.

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