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Delgrange, E., Trouillas, J., Maiter, D. et al. Sex-related difference in the growth of prolactinomas: a clinical and proliferation marker study. Journal of Clinical Endocrinology and Metabolism 1997, 82: 2102-2107.

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Article

Giant Prolactinoma: Case Report and Review of Literature

1Department of Endocrinology, King Fahad Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia


American Journal of Medical Case Reports. 2015, Vol. 3 No. 12, 399-402
DOI: 10.12691/ajmcr-3-12-4
Copyright © 2015 Science and Education Publishing

Cite this paper:
Khalid S.Aljabri, Samia A. Bokhari, Ahmad Akl. Giant Prolactinoma: Case Report and Review of Literature. American Journal of Medical Case Reports. 2015; 3(12):399-402. doi: 10.12691/ajmcr-3-12-4.

Correspondence to: Khalid  S.Aljabri, Department of Endocrinology, King Fahad Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia. Email: khalidsaljabri@yahoo.com

Abstract

Prolactin (PRL) secreting adenomas are the most common secreting pituitary tumors, accounting for approximately 45% of all pituitary tumours. Giant prolactinomas are a rare subset of macroadenomas, characterized by large size (more than 40 mm in diameter (an arbitrary size), high aggressiveness and massive extrasellar involvement. We describe an unusual giant prolactin producing macroadenoma of pituitary gland in female patients with type 2 diabetes mellitus and its response to cabergoline.

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