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Van Veggel M, Olofinjana O, Davies G, et al. Clozapine and gastro-oesophageal reflux disease—an investigation of temporal association. Acta Psychiatr Scand 2013 Jan 127 (1):69-77.

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Article

Hematemesis in a Child on Olanzapine

1Department of Emergency Medicine, Cooper University Hospital, Camden, NJ


American Journal of Medical Case Reports. 2015, Vol. 3 No. 11, 380-382
DOI: 10.12691/ajmcr-3-11-9
Copyright © 2015 Science and Education Publishing

Cite this paper:
Richard Pescatore DO, Dunisha Ranasuriya MD, Lisa Drago DO, Julie Whitney DO, Sandra Nairn DO. Hematemesis in a Child on Olanzapine. American Journal of Medical Case Reports. 2015; 3(11):380-382. doi: 10.12691/ajmcr-3-11-9.

Correspondence to: Richard  Pescatore DO, Department of Emergency Medicine, Cooper University Hospital, Camden, NJ. Email: Pescatore-richard@cooperhealth.edu

Abstract

The case of a 13-year old boy with hepatic steatosis secondary to atypical antipsychotic use is described. The patient presented with a single episode of moderate-volume hematemesis and was found to have severe fatty infiltration and ductal dilatation of the liver. These changes were attributed to the patient’s use of olanzapine for behavioral disorders related to autism spectrum disorder. The differential diagnosis of pediatric hematemesis is described, as well as the importance of considering adverse drug affects in patients maintained on olanzapine and other antipsychotics.

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