1Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University, Faculty of Medicine, Košice, Slovakia
2Department of Cardiovascular Surgery, Pavol Jozef Šafárik University, Faculty of Medicine and VUSCH, Košice, Slovakia
3Institute of Physics, Pavol Jozef Šafárik University, Faculty of Science, Košice, Slovakia
American Journal of Medical and Biological Research.
2015,
Vol. 3 No. 5, 128-132
DOI: 10.12691/ajmbr-3-5-2
Copyright © 2015 Science and Education PublishingCite this paper: Zuzana Guľašová, Vladimíra Tomečková, Miroslava Bilecová-Rabajdová, Beáta Veliká, Panayotis Artemiou, Vladimír Komanický, Mária Mareková. Monitoring of Thoracic Aortic Aneurysm in Blood by Fluorescence Spectroscopy.
American Journal of Medical and Biological Research. 2015; 3(5):128-132. doi: 10.12691/ajmbr-3-5-2.
Correspondence to: Zuzana Guľašová, Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University, Faculty of Medicine, Košice, Slovakia. Email:
gulasova.z@gmail.comAbstract
Components of the blood plasma and serum represent a mixture of various endogenous substances with fluorescence properties. The aim of this work was a detection of pathological changes in blood of patients with thoracic aortic aneurysm by fluorescence spectroscopy and atomic force microscopy. The resulting autofluorescence of fluorophores in blood of patients with thoracic aortic aneurysm decreased in comparison with healthy subjects. The structure of the thoracic aorta was changed during the thoracic aortic aneurysm, what was manifested as the structural modifications in blood of patients observed by using atomic force microscopy. The fluorescence analysis and atomic force microscopy present new experimental ways in the study of the thoracic aortic aneurysm.
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