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Lehman DA, Farquhar C. Biological mechanisms of vertical human immunodeficiency virus (HIV-1) transmission. Rev Med Virol. 2007;17: 381-403.

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Article

Feeding Options and Antiretroviral Prophylaxis among Exposed Infants in Bida, North Central Nigeria

1Department of Medical Microbiology, Federal Medical Centre Bida, Niger State, Nigeria

2Department of Nursing Services, Federal Medical Centre Bida, Niger State, Nigeria

3Department of Paediatrics Federal Medical Centre Bida, Niger State, Nigeria

4Department of Chemical Pathology Federal Medical Centre Bida, Niger State, Nigeria

5Department of Haematology Federal Medical Centre Bida, Niger State, Nigeria


American Journal of Epidemiology and Infectious Disease. 2015, Vol. 3 No. 2, 32-35
DOI: 10.12691/ajeid-3-2-3
Copyright © 2015 Science and Education Publishing

Cite this paper:
Ogedengbe Sunday Oladokun, Ogedengbe Dorcas Talatu, Inyinbor Henry Eromosele, Omosigho Omoruyi Pius, Akobi Oliver Adeymi, Emumwen Evbaziegbere Gideon, Mohammed Kudu Sheu, Eze Edith Chinwe, Oladejo Olayinka Paul, Uzoigwe Eunice Ogochukwu, Abayomi Rachael Oluwafunmilayo, Akpabio Nse Sunday, Salami Abubakar, Okorie Eucheria. Feeding Options and Antiretroviral Prophylaxis among Exposed Infants in Bida, North Central Nigeria. American Journal of Epidemiology and Infectious Disease. 2015; 3(2):32-35. doi: 10.12691/ajeid-3-2-3.

Correspondence to: Ogedengbe  Sunday Oladokun, Department of Medical Microbiology, Federal Medical Centre Bida, Niger State, Nigeria. Email: sunday_ogedenbge@yahoo.com

Abstract

Background: Breastfeeding is a major health promoting factor in infants and children in developing countries, but the risk of mother-to-child transmission (MTCT) of HIV by this route is challenging traditional and health policies in low resource countries. Aims: The aim of the study is to determine the effect of feeding options and infant antiretroviral prophylaxis on transmission of HIV in Bida North Central Nigeria. Patients and methods: we reviewed a total of Four hundred and fourteen (414) HIV exposed infants whose dried blood spot (DBS) samples were taken for DNA PCR test between May 2011 and July 2013 and whose parents are on antiretroviral therapy and for whom a complete set of records were available. Results: The most prevalent feeding option was mixed feeding 250(60.4%) followed by exclusive breastfeeding 84(20.3%) and exclusive formula feeding 80(19.3%). The HIV transmission rate is higher among mixed feeding 17.6% followed by exclusive breastfeeding 7.1% and exclusive formula feeding 5.0%. HIV transmission rate of 6.0% was observed for infants that were on antiretroviral prophylaxis and 43.6% for infants who were not on antiretroviral prophylaxis. Conclusion: The study shows the benefits of exclusive formula feeding and the intake of antiretroviral prophylaxis in reducing HIV transmission through breastfeeding.

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