Leidiane de Lucca¹, Francisco Maximiliano Pancich Gallarreta², Thissiane de Lima Gonçalves^1,

Preeclampsia is a very important multisystem disorder to be specific to pregnancy, it is a disease mainly characterized by hypertension and proteinuria, but with unknown etiology that exposes the mother and the newborn to serious risks. One of the main factors involved in the pathophysiology of preeclampsia is oxidative stress and the rate of oxidative stress is measured by the ratio between the reactive oxygen species produced in the body called free radicals, and antioxidants produced by the body or absorbed through the diet. The excess of these free radicals have harmful effects, such as peroxidation of membrane lipids and aggression to tissue and membranes proteins as well as to membranes, enzymes, carbohydrates and DNA. Hypertensive disorders in pregnancy are a major cause of morbidity and maternal and fetal mortality. Preeclampsia is classified as a type of hypertensive complication that affects many pregnant women worldwide. The pregnancy and preeclampsia are conditions that increase susceptibility to oxidative stress, which in turn contributes to numerous complications, further aggravating the condition.

Oxidative Stress, Pregnancy, Preeclampsia, Biomarkers