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Article

Prognostic Significance of Serum Uric Acid at the Time of Admission in Patients with Acute Stroke

1Department of accident and emergency, Lady Hardinge Medical College, New Delhi

2Department of Internal Medicine, IPGMER, Kolkata

3Department of Internal Medicine, RG Kar Medical College, Kolkata


American Journal of Clinical Medicine Research. 2015, Vol. 3 No. 2, 24-30
DOI: 10.12691/ajcmr-3-2-2
Copyright © 2015 Science and Education Publishing

Cite this paper:
Dhrubajyoti Bandyopadhyay, Adrija Hajra, Sabyasachi Mukhopadhyay, Manas Layek, Diptak Bhowmick, Vijayan Ganeshan, Sibnarayan Sasmal, Debarati Bhar, Cankatikachoudhury, Partha Sarathi Karmakar. Prognostic Significance of Serum Uric Acid at the Time of Admission in Patients with Acute Stroke. American Journal of Clinical Medicine Research. 2015; 3(2):24-30. doi: 10.12691/ajcmr-3-2-2.

Correspondence to: Dhrubajyoti  Bandyopadhyay, Department of accident and emergency, Lady Hardinge Medical College, New Delhi. Email: drdhrubajyoti87@gmail.com

Abstract

Background & objectives: Stroke is the one of the important causes of death.Uric acid is described as a strong endogenous antioxidant that is consumed early in acute stroke. Uric acid being an aqueous antioxidant can become a pro-oxidant under certain circumstances, particularly, if other antioxidants such as ascorbate are low. This work was conducted to find an association between serum uric acid levels at the time of admission with functional outcome in patients with acute stroke. Method: This study was carried out on 96 patients of stroke including both ischemic and hemorrhagic stroke. Sampling scheduled one day of the week by rotation to avoid selection bias and the study design was descriptive, observational, cross-sectional study. Result: we found statistically significant positive correlation between serum uric acid level and change in Mathew score in ischemic stroke patients and poor positive correlation between uric acid level and change of Mathew score in hemorrhagic stroke patients. Conclusion: High serum uric acid level is associated with good neurological outcome in patients with acute ischemic stroke. A high serum uric acid level is associated with insignificant poor neurological outcome in patients with hemorrhagic stroke.

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