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Smolen JS, Steiner G. Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discov 2003; 2(6):473-488.

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Article

Rheumatoid Arthritis: An Exceptional Complication of Chemotherapy in a Patient with Lung Cancer

1Department of Nuclear Medicine, Taipei Veterans General Hospital, Taiwan

2National Yang-Ming University School of Medicine, Taiwan;National Defense Medical Center, Taipei, Taiwan


American Journal of Medical Case Reports. 2015, Vol. 3 No. 5, 130-132
DOI: 10.12691/ajmcr-3-5-3
Copyright © 2015 Science and Education Publishing

Cite this paper:
Tse-Hao Lee, Rong-Hsin Yang, Yum-Kung Chu. Rheumatoid Arthritis: An Exceptional Complication of Chemotherapy in a Patient with Lung Cancer. American Journal of Medical Case Reports. 2015; 3(5):130-132. doi: 10.12691/ajmcr-3-5-3.

Correspondence to: Yum-Kung  Chu, Department of Nuclear Medicine, Taipei Veterans General Hospital, Taiwan. Email: ykchu@vghtpe.gov.tw

Abstract

A 63-year-old non-smoker, without previous history of arthritis, developed inflammatory arthritis while being treated with pemetrexed/cisplatin combination for advanced lung cancer. Clinical features and serology fulfilled the 2010 ACR/EULAR criteria for the diagnosis of rheumatoid arthritis (RA). RA is an autoimmune disease that primarily attacks joint tissues, causing inflammation of the joint lining. Although the relationship between these anticancer agents and the presence of RA remains unclear, this unprecedented adverse effect can be corrected by changing therapeutic strategies. Our case report might open a medical debate about chemotherapy side effect in cancer patients.

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