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Karesj JW, Goldman EJ, Reck K, Kelman S.E, Lee E.J, Schiffer C.A. A prospective ophthalmic evaluation of patients with acute myeloid leukemia: correlation of ocular and hematologic findings. J Clin Oncol. 7 (10). 1528-1532. 1989.

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Article

A Case of Acute Myeloid Leukemia with Bilateral Leukemic Optic Nerve Infiltration

1Atatürk University, School of Medicine, Departments of Haematology, Erzurum, TURKEY

2Atatürk University, School of Medicine, Departments of Internal Medicine, Erzurum, TURKEY

3Atatürk University, School of Medicine, Departments of Radiology, Erzurum, TURKEY


American Journal of Medical Case Reports. 2015, Vol. 3 No. 4, 111-112
DOI: 10.12691/ajmcr-3-4-7
Copyright © 2015 Science and Education Publishing

Cite this paper:
Yıldırım Rahşan, Urlu Selin Merih, Sincan Gülden, Kaban Göktürk, Karaman Adem, Bilen Yusuf. A Case of Acute Myeloid Leukemia with Bilateral Leukemic Optic Nerve Infiltration. American Journal of Medical Case Reports. 2015; 3(4):111-112. doi: 10.12691/ajmcr-3-4-7.

Correspondence to: Sincan  Gülden, Atatürk University, School of Medicine, Departments of Haematology, Erzurum, TURKEY. Email: guldensincan@gmail.com

Abstract

Ocular involvement in patients with leukemia may be due to various reasons and it is characterized by various clinical symptoms. Ocular problems in patients who have acute myeloid leukaemia (AML) are commonly observed. Orbital and ocular lesions carry a poor prognosis in patients with acute myeloid leukemia. Direct invasion of the retina and choroid with the neoplastic cells is common, but the involvement of the optic nerve, uveal tract are relatively rare. Ocular symptoms include blurred vision and diplopia due to the involvement of optic nerves. This paper reports a 68 year old patient with AML. 5 azasitidin was initiated for treatment. By the second cycle, he complained of vision loss for right eye. These findings occured for left eye after three days. Optic nerve involvement was found with orbital magnetic resonance imaging with contrast. We report these patient because of rarity.

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