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Caproni M, Bonciolini V, D'Errico A, Antiga E, Fabbri P. Celiac disease and dermatologic manifestations: many skin clue to unfold gluten-sensitive enteropathy.Gastroenterol Res Pract. 2012; 2012: 952753.

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Article

Celiac Disease: Intestinal, Heart and Skin Interconnections

1Pediatric Gastroenterology and Nutrition Unit, Carmel Medical Center, B, Rappaport School of Medicine, Technion-Israel institute of Technology, Haifa, Israel

2Aesku.Kipp Institute, Wendelsheim, Germany


International Journal of Celiac Disease. 2015, Vol. 3 No. 1, 28-30
DOI: 10.12691/ijcd-3-1-6
Copyright © 2015 Science and Education Publishing

Cite this paper:
Aaron Lerner, Torsten Matthias. Celiac Disease: Intestinal, Heart and Skin Interconnections. International Journal of Celiac Disease. 2015; 3(1):28-30. doi: 10.12691/ijcd-3-1-6.

Correspondence to: Aaron  Lerner, Pediatric Gastroenterology and Nutrition Unit, Carmel Medical Center, B, Rappaport School of Medicine, Technion-Israel institute of Technology, Haifa, Israel. Email: aaronlerner1948@gmail.com

Abstract

The first description of celiac disease associated with dilated cardiomyopathy and pellagra in the same person, brings multiple interesting aspects to discuss. Celiac disease is prevalent in cardiac failure and vice versa, multiple cardiac manifestations exist in celiac disease. Pathophysiologically, autoimmune, nutritional, infectious and thrombophilic pathways can be involved. In some cases the cardiomyopathy respond to gluten free diet. Multiple cutaneous manifestations, including pellagra like rash, were described in CD. Autoimmune mechanisms and much more, (e.g. nutrient deficiencies) might aggravate the skin manifestation. The present editorial highlights the cardiac-cutaneous-intestinal cross talks in celiac disease in order to increase the awareness of the physician community to speed up celiac disease diagnosis in those extraintestinal manifestations.

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