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Gregory K., “Current Understanding of Delayed Anticonvulsant Hypersensitivity Reactions”. Epilepsy Currents, 6(2), 33–37, 2006.

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Article

Recent Advances in Development of Sulfonamide Derivatives and Their Pharmacological Effects- A Review

1Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, IFTM University, Moradabad Uttar Pradesh, India

2Department of Pharmaceutical Chemistry, S. D. College of Pharmacy and Vocational Studies, Muzaffarnagar, Uttar Pradesh, India


American Journal of Pharmacological Sciences. 2015, Vol. 3 No. 1, 18-24
DOI: 10.12691/ajps-3-1-4
Copyright © 2015 Science and Education Publishing

Cite this paper:
Ajeet, Arun K. Mishra, Arvind Kumar. Recent Advances in Development of Sulfonamide Derivatives and Their Pharmacological Effects- A Review. American Journal of Pharmacological Sciences. 2015; 3(1):18-24. doi: 10.12691/ajps-3-1-4.

Correspondence to:  Ajeet, Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, IFTM University, Moradabad Uttar Pradesh, India. Email: ajeet_pharma111@rediffmail.com

Abstract

First drugs which were largely used for chemotherapeutically and preventive use were the sulfonamides. Sulfonamides have a wide range of pharmacological activities such as against rheumatoid arthritis, anti-hypertensive, anti-epileptic, anti-bacterial, anti-protozoal, anti-fungal, non-peptidic vasopressin receptor antagonists, anti-inflammatory, and translation initiation inhibitors. These sulfonamides have a variety of synthetic reactions to work with. This review comprises of recent advances related to synthesis and pharmacological effects of sulfonamides especially in concern to anti-epileptic and anti-microbial agents.

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