@article{wjoc2021913,
author={{Liao, Xiaojian and Zhou, Yuemin and Tang, Fu and Lin, Xia and Li, Yiqun},
title={Carboxymethylcellulose-supported Palladium Nanoparticles Formed <i>in situ</i> for Suzuki-Miyaura Coupling Reaction},
journal={World Journal of Organic Chemistry},
volume={9},
number={1},
pages={18--28},
year={2021},
url={http://pubs.sciepub.com/wjoc/9/1/3},
issn={2372-2169},
abstract={A green experiment is described here for direct fabrication of carboxymethylcellulose-supported palladium nanoparticles (PdNPs@CMC) <i>in situ</i> through a simple self-assemble and self-reduction process between carboxymethylcellulose (CMC-Na) and PdCl<SUB>2</SUB> solution. The PdNPs@CMC was well characterized by ICP, UV-Vis, XPS, FTIR, SEM, and TEM techniques. The <i>in situ</i> synthesized PdNPs@CMC was proved to be an efficient catalyst for Suzuki-Miyaura coupling reaction under mild aerobic conditions. The superior catalytic performance of PdNPs@CMC is attributed to the coordination with carboxyl groups (?COO<SUP>?</SUP>) and free hydroxyl groups (?OH) as well as polymeric capping effect of CMC. Moreover, the catalyst showed no significant loss of its activity at least three consecutive cycles. This laboratory class is involved in the preparation and characterization of PdNPs@CMC as well as its catalytic application in Suzuki?Miyaura cross coupling reaction under green conditions. This laboratory class is suggested to divide into two parts. The first part includes the fabrication of catalyst <i>in situ</i> through a self-assemble and self-reduction of Pd(II) with CMC?Na, and characterization of the as-prepared catalyst using various techniques. The second part employs the resulting catalyst to perform a microscale Suzuki-Miyaura reaction, recycling of catalyst, and characterization of the product. By design, this comprehensive experiment set up for the third-year undergraduate, and aim to make students comprehend the concept of ion-exchange reaction, reduction reaction, carbon-carbon coupling reaction, supported catalysts, nanoparticles, and green chemistry as well as train the fundamental operation capability of students, and improve their experimental skills. <img src=image/abs1.png></img>},
doi={10.12691/wjoc-9-1-3}
publisher={Science and Education Publishing}
}