@article{wjoc2018613,
author={{Mottaghinejad, Enayatollah and Alibakhshi, Shabnam},
title={Synthesis of Novel Triazole Derivatives Based on 4-methyl-chromene-2-one},
journal={World Journal of Organic Chemistry},
volume={6},
number={1},
pages={13--15},
year={2018},
url={http://pubs.sciepub.com/wjoc/6/1/3},
issn={2372-2169},
abstract={Synthesis of 1,2,4- triazoles fused to another heterocyclic ring such as pyridine, pyridazine, pryimidine, pyrazine and triazine are very well known systems with diverse biological application. In this research the 4-methyl-2-oxo-2H-chromen-7-yl-oxyacetic acid ethyl ester was prepared as the key starting material according to the known procedures. Treatment of 4-methyl-2-oxo-2H-chromen-7-yl-oxyacetic acid ethyl ester with hydrazine hydrate afford 4-methyl-2-oxo-2H-chromen-7-yl-oxyacetic acid hydrazide. At the last stage, the prepared 4-methyl-2-oxo-2H-chromen-7-yl-oxyacetic acid hydrazide was reacted in situ with benzaldehyde and their derivatives in the presense of ammonium acetate using acetic acid as solvent. The final triazole products was obtained with excellent yield. The structures of the target compounds confirmed by IR, <SUP>1</SUP>H-NMR, <SUP>13</SUP>C-NMR, and MASS analysis.},
doi={10.12691/wjoc-6-1-3}
publisher={Science and Education Publishing}
}