@article{wjoc2018611,
author={{Alam, Mohammad Mahboob and Zabin, Sami A. and Nazreen, Syed},
title={<i>In</i><i> </i><i>vitro</i> Antimicrobial Efficiency of Crude Extracts of Wild<i> </i><i>Jatropha</i><i> </i><i>glauca</i> Plant Leaves Grown Naturally at Al-Baha Region, KSA},
journal={World Journal of Organic Chemistry},
volume={6},
number={1},
pages={1--5},
year={2018},
url={http://pubs.sciepub.com/wjoc/6/1/1},
issn={2372-2169},
abstract={The crude extracts from leaves of <i>Jatropha</i><i> </i><i>glauca</i> plant grown naturally at Al-Baha region obtained by extraction with ethanol and fractionated using three solvents: petroleum ether, ethyl acetate and methanol were investigated for their <i>in</i><i> </i><i>vitro</i> antimicrobial susceptibility. The antimicrobial activity were evaluated against two bacterial strains<i> </i><i>S.</i><i> </i><i>aureus</i> <i>and</i><i> </i><i>E.</i><i> </i><i>coli</i>, and two common fungal strains <i>Candida</i><i> </i><i>albicans</i> and<i> </i><i>Candida</i><i> </i><i>krusei</i> using disc diffusion assay. The crude ethanolic extract and its fractions methanolic and ethyl acetate showed an inhibitory effect against both bacterial and fungal microorganisms. The petroleum ether fraction had no antimicrobial effect. The ethanolic crude extract and methanolic fraction showed higher zone of inhibition, while the ethyl acetate fraction showed the least activity against both bacterial strains. The methanolic fraction was found to possess lowest MIC ¡Ý250 ¦Ìgml<SUP>?1</SUP><SUP> </SUP>against both tested bacterial strains. Similarly, the ethanolic crude extract and methanol fraction showed zone of inhibition against tested fungal strains with methanolic fraction showed the highest zone of inhibition. However, these observations indicated that the ethanolic crude extract and its methanolic and ethyl acetate fractions exhibited some antimicrobial potency that proves the leaves contain some gradients that have antibacterial and antifungal potential.},
doi={10.12691/wjoc-6-1-1}
publisher={Science and Education Publishing}
}