@article{wjoc2014211,
author={Mohamed, Hany M.},
title={A Convenient Synthesis of Ethyl 1-Amino-3-(Substituted Phenyl)-2-Cyano-3<i>H</i>-Benzo[4,5]Thiazolo-[3,2-<i>a</i>]Pyridine-4-Carboxylate Derivatives and Some of their Reactions},
journal={World Journal of Organic Chemistry},
volume={2},
number={1},
pages={1--8},
year={2014},
url={http://pubs.sciepub.com/wjoc/2/1/1},
abstract={The titled compounds were prepared by interaction of ethyl 2-(benzo[<i>d</i>]thazol-2-yl)acetate <b>(3)</b> with different arylidinemalononitrile derivatives <b>(4a-c)</b> in EtOH/TEA solution at room temperature. When <b>3</b> was treated with 2-(ethoxymethylene)-malononitrile <b>(4f) </b>under same reaction conditions, the ethyl iminothiazolopyridine-4-carboxylate <b>(6)</b> was obtained. Ethyl (amino(methoxy)methyl)-3-(substitutedphenyl)-1-oxo-1<i>H</i>-benzo[4,5]thiazole[3,2-<i>a</i>]pyridine-4-carboxylate <b>(8a,b)</b><b> </b>was obtained from reaction of <b>3</b> with different cyanoacrylate derivatives <b>(7a,b) </b>in MeOH/TEA at room temperature, while the diethyl thiazolo[3,2-<i>a</i>]pyridine-4-carboxylate derivative <b>(8c) </b>was obtained under same reaction conditions. The amino-imino derivative <b>(10)</b> was also prepared and used to synthesis new pyrido[3,2-<i>e</i>][1,2,4]triaziolo[1,5-<i>c</i>]pyrimidine-5-carboxylate derivatives <b>(12)</b>. The structures of all the newly synthesized compounds were confirmed based on their elemental analysis and spectroscopic data.},
doi={10.12691/wjoc-2-1-1}
publisher={Science and Education Publishing}
}