eng Science and Education Publishing World Journal of Organic Chemistry 2013-04-23 1 1 20 23 10.12691/wjoc-1-2-3 WJOC2013123 article Nathalie Berezina nathalie.berezina@materianova.be 1 Nicolas Landercy 1 Pierre-Antoine Mariage 2 3 Benoit Morea 3 Green Chemistry Department, Materia Nova R&D Center, Ghislenghien, Belgium R&D Department, Galactic SA, Escanaffles, Belgium Despite the small difference in the steric hindrance of the substitutes of the asymmetric carbon of the lactic acid, a way for the desymmetrization of the racemic mixture was discovered. Two possibilities have arisen: the synthesis and further separation of diastereoisomers with the (S)-2-methyl-1-butanol as chiral auxiliary and the kinetic discrimination during the esterification with the (R)-(-)-Myrtenol. http://pubs.sciepub.com/wjoc/1/2/3/wjoc-1-2-3.pdf lactide enantiomeric separation diastereoisomers PLA bioplastics