@article{wjce2019735,
author={{Waddell, Michelle K. and Bump, Charles M. and Ndip, Edmund M. and Nwokogu, Godson C.},
title={Determination of the <i>p</i>/<i>o</i>-Isomer Product Ratios in Electrophilic Aromatic Nitration of Alkylbenzenes Using High Resolution <SUP>1</SUP>H NMR Spectroscopy},
journal={World Journal of Chemical Education},
volume={7},
number={3},
pages={216--224},
year={2019},
url={http://pubs.sciepub.com/wjce/7/3/5},
issn={2375-1657},
abstract={High resolution <SUP>1</SUP>H NMR spectroscopy, an increasingly available instrumental method, is used in undergraduate organic laboratory practice as a simpler alternative to gas chromatographic method for the direct determination of the <i>p</i>/<i>o</i> ratios of the crude reaction product from the nitration of alkylbenzenes. The choice of isopropylbenzene as a substrate illustrates that steric effect can be significant in controlling regioselectivity in electrophilic aromatic substitution reactions.},
doi={10.12691/wjce-7-3-5}
publisher={Science and Education Publishing}
}
