eng Science and Education Publishing World Journal of Chemical Education 2375-1657 2017-05-02 5 3 102 106 10.12691/wjce-5-3-4 WJCE2017534 article A. Habekost A.Habekost@t-online.de 1 University of Education Ludwigsburg, Department of Chemistry, Reuteallee 46, D-71634 Ludwigsburg, Germany We present experiments that show the inhibition of the catalytic activity of the enzyme urease on the chemical degradation of urea with copper ions. In addition, we demonstrate the efficiency of the antidotes 2,3-dimercapto-1-propanesulfonic acid (DMPS, 2,3-bis(sulfanyl)propane-1-sulfonic acid) and 2,5-dimercapto-1,3,4-thiadiazole (DMTD) on reactivation of urease by complexation of copper. http://pubs.sciepub.com/wjce/5/3/4/wjce-5-3-4.pdf three-year undergraduate analytical electrochemistry electrochemiluminescence IR-spectrometry hands-on learning/manipulatives