Science and Education Publishing Research in Psychology and Behavioral Sciences 2333-438X 4 2 2016 8 30 The Correlates of Quality Of Life among Jordanian Patients with Major Depressive Disorder 28 33 EN Ahmad Rayan Psychiatric and Mental Health Nursing, Zarqa University Maryam Husnee Mahroum RPBS2016423 10.12691/rpbs-4-2-3 2016 4 15 2016 6 19 2016 8 28 Background: Despite the increasing rates of patients diagnosed with major depression in Jordan, there is little knowledge available about the factors associated with quality of life (QOL) among this population in particular. This knowledge is needed to implement relevant supporting programs to improve their quality of life. Purpose: This study aims to assess the level of quality of life among Jordanian patients with major depressive disorder, and to examine the possible relationship between quality of life and other factors (demographic variables, stigma of mental illness, and severity of depressive symptoms) in this population. Methodology of the Study: A descriptive correlational design was used. A convenience sample of 161 Jordanian outpatients suffering from Major Depression Disorder (MDD) completed the study. Participants completed the demographic questionnaire, the Center for Epidemiologic Studies Depression Scale (CES-D), Percieved Devaluation-Discrimination Scale, and Medical Outcomes Study 36-item Short Form (SF-36). Results: Participants reported poor QOL in all domains. Age, income, stigma toward mental illness, and severity of depressive symptoms were significantly correlated with QOL among the study sample. Multiple hierarchical regression analysis revealed that the severity of depressive symptoms is the strongest correlate of QOL, which accounted for 24% additional variance above and beyond the 18% variance accounted for by all other variables. Conclusion: This is the first study to assess QOL in an Arab population with major depression. Replication of the current study in other Arab samples is emphasized. Psychotherapy and other interventions are still needed even after the acute symptoms of the clinical depression are remitted.