Science and Education Publishing Oral Surgery, Oral Medicine, Oral Radiology 3 1 2015 08 02 The Effect of Mouth Rinsing with Stabilized Chlorine Dioxide on Periodontitis 20 24 EN Shuichi Tsubura Department of Biochemistry, The Nippon Dental University School of Life Dentistry at Niigata, Hamaura-cho, Chuo-ku, Niigata, Japan Kimio Uchiyama Manabu Yamada Osamu Mimori Shigeru Hiyama Katsuma Katoh Masaki Shibata ORAL2015315 10.12691/oral-3-1-5 2015 07 05 2015 07 26 2015 08 02 MATATACOROTM (containing 10 mg/l stabilized chlorine dioxide: MA-T, no alcohol, and is an odorless antibacterial agent) is useful for sterilization and disinfection. The aim of this study was to investigate whether MA-T is an appropriate mouth rinse for patients selected from whom undergoing initial periodontal treatment. The effect of rinsing with MA-T was compared with that with ConcoolTM (containing 0.05% chlorhexidine gluconate: CX), Neosterine GreenTM (containing 0.02% benzethonium chloride: NG), and purified water (PW). MA-T rinsing resulted in a marked change in the BANA-score and in the VAS scale. The mean BANA scores (score ± SD) on day 0 and day 30 were 1.550.50 and 0.40.50 (p<0.001) for MA-T, 1.650.48 and 0.750.44 for CX, 1.430.50 and 0.880.61 for NG, and 1.830.38 and 1.480.55 for PW, respectively. The intra-oral feeling caused by mouth rinsing was self-assessed using the VAS scores (mean ± SD) on day 0 and day 30; they were 48.2314.70 and 74.437.33 (26.2 mm increase) for MA-T, 50.4511.94 and 62.238.88 (11.8 mm increase) for CX, 54.138.11 and 63.738.18 (9.6 mm increase) for NG, and 54.706.06 and 59.186.11 (4.5 mm increase) for PW, respectively. These results suggest that MA-T induced marked reduction of periodontopathic oral bacteria and increased feeling of freshness after the treatment period. These results suggest that MA-T is an appropriate mouth rinse for patient with periodontitis.