eng Science and Education Publishing Oral Surgery, Oral Medicine, Oral Radiology 2015-08-02 3 1 20 24 10.12691/oral-3-1-5 ORAL2015315 article Shuichi Tsubura tshu@ucatv.ne.jp 1 2 Kimio Uchiyama 2 3 Manabu Yamada 3 Osamu Mimori 3 Shigeru Hiyama 3 Katsuma Katoh 3 Masaki Shibata 3 Department of Biochemistry, The Nippon Dental University School of Life Dentistry at Niigata, Hamaura-cho, Chuo-ku, Niigata, Japan MATATACOROTM (containing 10 mg/l stabilized chlorine dioxide: MA-T, no alcohol, and is an odorless antibacterial agent) is useful for sterilization and disinfection. The aim of this study was to investigate whether MA-T is an appropriate mouth rinse for patients selected from whom undergoing initial periodontal treatment. The effect of rinsing with MA-T was compared with that with ConcoolTM (containing 0.05% chlorhexidine gluconate: CX), Neosterine GreenTM (containing 0.02% benzethonium chloride: NG), and purified water (PW). MA-T rinsing resulted in a marked change in the BANA-score and in the VAS scale. The mean BANA scores (score ± SD) on day 0 and day 30 were 1.550.50 and 0.40.50 (p<0.001) for MA-T, 1.650.48 and 0.750.44 for CX, 1.430.50 and 0.880.61 for NG, and 1.830.38 and 1.480.55 for PW, respectively. The intra-oral feeling caused by mouth rinsing was self-assessed using the VAS scores (mean ± SD) on day 0 and day 30; they were 48.2314.70 and 74.437.33 (26.2 mm increase) for MA-T, 50.4511.94 and 62.238.88 (11.8 mm increase) for CX, 54.138.11 and 63.738.18 (9.6 mm increase) for NG, and 54.706.06 and 59.186.11 (4.5 mm increase) for PW, respectively. These results suggest that MA-T induced marked reduction of periodontopathic oral bacteria and increased feeling of freshness after the treatment period. These results suggest that MA-T is an appropriate mouth rinse for patient with periodontitis. http://pubs.sciepub.com/oral/3/1/5/oral-3-1-5.pdf stabilized chlorine dioxide mouth rinse periodontitis oral bacteria freshness