eng Science and Education Publishing Neuro-Ophthalmology & Visual Neuroscience 2015-05-03 1 1 27 36 10.12691/novn-1-1-6 NOVN2015116 article Carlo Aleci carlo.aleci@unito.it 1 2 Carlo Mannone 3 Nicoletta Rebaudengo 4 The Gradenigo Hospital, Department of Ophthalmology, Turin, Italy Medical Centre 50, Boulevard des belges, Lyon, France The Gradenigo Hospital, Department of Neurology, Turin, Italy Similarity in embryological development, anatomical and structural organization as well as chemical physical properties of organs and apparatus makes them common targets for specific pathological events. Such multi-involvement could well be the case of the cerebrospinal and aqueous circulatory systems, respectively in the brain ventricles and in the anterior and posterior chamber of the eye. After having described the resemblances in secretion, circulation, absorption and composition of the ventricular cerebrospinal fluid and of the ocular aqueous humor, a joint classification of their pathological involvement, namely hydrocephalus and glaucoma, is advanced. Finally, based on our preliminary results, morpho-functional alterations of the ventricular fluid dynamics leading to communicant hydrocephalus is suggested to affect to a certain extent the ocular hydrodynamics as well, predisposing the eye to ocular hypertension. http://pubs.sciepub.com/novn/1/1/6/novn-1-1-6.pdf ventricles anterior chamber posterior chamber aqueous humor cerebrospinal fluid hydrocephalus glaucoma ocular hypertension