eng Science and Education Publishing Journal of Physical Activity Research 2016-12-24 2 1 1 6 10.12691/jpar-2-1-1 JPAR2017211 article Nestor Asiamah nestor.asiamah@yahoo.com 1 Henry Kofi Mensah 2 Research, Africa Center for Epidemiology, Accra, Ghana Kwame Nkrumah University of Science and Technology, Kumasi, Ghana Working long hours is often said to be associated with depression. Research has also shown that physical activity is a remedy for depression. If this is the case, work involving an adequate level of physical activity may reduce depression. This study therefore examines the association between work-related physical activity and depression. A cross-sectional quantitative research design was applied. Three groups of workers having varied physical activity levels were compared. Each group had 218 volunteer participants. Analysis of Variance and a linear contrasts test were used to present results. Data analysis shows that sedentary jobs have the highest level of depression (Mean = 26.03, SD = 10.24, 95%CI = 25.26-27.80). Partially sedentary jobs produce a depression level higher than SEDJOB but lower than PHYJOB (Mean = 15.867, SD = 7.49, 95%CI = 14.9, 16.9). Physical jobs produce the lowest level of depression (Mean = 11.119, SD = 6.26, 95%CI = 10.3, 12.0). The study thus finds a statistically significant negative association between work-related physical activity and depression at 1% significance level. Thus, depression decreases with increased work-related physical activity. It may therefore be necessary for organizations to implement systems that encourage workers to regularly engage in work-related physical activity. They may have to create recreation centers (e.g. Gyms) where workers can exercise after hours of work in sedentary conditions. http://pubs.sciepub.com/jpar/2/1/1/jpar-2-1-1.pdf physical activity work-related physical activity sedentary behavior depression