Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
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Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

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David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

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David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
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Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Label_Title

Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Adsorption Behavior of Copper and Paracetamol Residues in Removal Strategy from Hospital Wastewater on Beninese Kaolinite Surface

François Zagabe Zabene, Simplice Koudjina*, Alidor Mbaya Shikika, Ferdinand Goudjo, Nafiou Egbeola Chitou, Jean Wilfried Hounfodji, Etienne Sagbo, Fabrice Amisi Muvundja, Waris Kewouyemi Chouti

National High School of Applied Biosciences and Biotechnologies (ENSBBA) National University of Sciences, Technologies, Engineering and Mathematics (UNSTIM), BP 486 Abomey, Sogbo-Aliho – Benin

Abstract: Heavy metal and drug residues in the environmental have become serious pollutants to be addressed. Grey waters from municipalities, hospitals and chemical industries may be loaded with these chemicals and end up into the environment, especially in water springs, rivers and lakes. Moreover, the pre-treatment measures for these wastewaters are needed to ensure the treated water is environmentally safe and unpolluted. Therefore, we aimed in this work to optimize the physicochemical conditions that favour their adsorption onto Beninese Kaolinite geopolymer from Ketou. Moreover, a quantum chemical mechanistic modeling showed that the adsorption of copper and paracetamol is exothermic according to a single mode for copper with an energy of -139.15 kJ.mol⁻¹ while that of paracetamol is in two modes, namely the horizontal mode having a high energy of -159.40 kJ.mol⁻¹, and the vertical mode of -91.10 kJ.mol⁻¹. By heating the kaolinite that had adsorbed these pollutants, it can release them at 435 K and 750 K respectively. Under these conditions, the geopolymer eliminates about 90% of the Cu²⁺ ions and 72% of the paracetamol. This adsorption process does not cause any disorder in its structure (∆S < 0), as follow the Pseudo-second order model with R² > 0.99 and its isotherms are well simulated by Langmuir model. Application to hospital wastewater gave reduction rates in copper of 90.5 ± 2.1% and in paracetamol of 88.5 ± 3.65%. Kaolinite was found to be an effective adsorbent for treating industrial wastewater before its discharge into the environment.

Keywords: Adsorption, Kaolinite, Copper, Paracetamol, Wastewater

Received April 08, 2024; Revised May 10, 2024; Accepted May 17, 2024

Citation: François Zagabe Zabene, Simplice Koudjina, Alidor Mbaya Shikika, Ferdinand Goudjo, Nafiou Egbeola Chitou, Jean Wilfried Hounfodji, Etienne Sagbo, Fabrice Amisi Muvundja, Waris Kewouyemi Chouti, Adsorption Behavior of Copper and Paracetamol Residues in Removal Strategy from Hospital Wastewater on Beninese Kaolinite Surface. Journal of Materials Physics and Chemistry, 12 (2). 22-30. January 2024. doi:10.12691/jmpc-12-2-1

1. Introduction

Numerous clay deposits in Benin can be exploited for industrial water purification. These clay minerals are often used in pottery, in the construction of adobe walls and in the industrial manufacture of bricks [1]. Kaolinite predominates in the commune of Ketou, located in the Plateau Department. The geopolymer developed by Dazogbo et al. [2], from Kaolinite collected in the same commune showed maximum absorption of Methyl Blue at pH 4.2 with an adsorption yield of 80%. Based on the results of the elimination of organic dyes (methyl blue) by geopolymers manufactured from kaolinite, we were motivated to study their capacities to eliminate Trace Metal Elements (TME) and Drugs Residues (DR) products as well as the analytical conditions that enable to obtain the best yields (optimization) and validate the optimised protocol through its application to the industrial wastewater treatment. Furthermore, there are several sources of TME and DR in these environments, but liquid discharges are the main source with industry being the major contributor [3]. As some authors have pointed out, industrial wastewater in Benin ends up in the sea or in freshwater bodies [4] although some factories such as Beninese Company for Industrial Transformations have some wastewater treatment plants and yet industrialisation has developed considerably in the case of the textile 0000industry, metallurgical and chemical industries respectively. Water resources pollution by TME in Benin is already a reality and found that water from wells and boreholes used to water crops at the Houeyiho market garden site in Cotonou was contaminated with Cd, Pb and Mn [5]. The levels of heavy metals in fish products from Lake Nokoue exceed the tolerated threshold for lead and copper for fish and shrimp samples (2.85 mg/kg) [4]. Among the pharmaceutical products on the Beninese market such as aspirin residues, paracetamol, ibuprofen, diazepam, diclofenac and carbamazepine are the most commonly found in environmental matrix [6]. In the aquatic environment, these risks can lead to sex reversal of fish males [7], kidney damage and altered gills caused by diclofenac [8], neuroteratogenic effects for humans, cancer and many other diseases. Under these conditions, prevention is the only efficient way to limit the consequences of the degradation of water resources and to preserve the environment through treatment.

Although, there are several widely adopted wastewater treatment methods (e.g. reverse osmosis, electrochemical treatment, adsorption), the most effective way of limiting contamination of water resources involves the development of an adsorption technique [9,10]. Moreover, clays are promising alternative and are of great interest in the elimination of heavy metals from wastewater. Since adsorption is a function of several parameters (pH, temperature, particle size, mass ratio, initial concentration, stirring speed, etc.) and the yield varies according to the variation in one or the other parameter, it becomes necessary to determine the operating conditions of the method using an optimization approach in order to make it more cost-effective and applicable.

This study aims to optimise the fixation of TME and DR on kaolinite in order to improve the method applicability by increasing the adsorption yield. More specifically, we have theoretically determined the adsorption mechanisms of copper and paracetamol on Kaolinite crystalline surface by Quantum Chemical Strategies from VASP software and experimentally from optimal parameters, kinetic and isotherm models for the adsorption of TME and DR onto the kaolinite-based geopolymer.

2. Material and Methods

2.1. Sample Site Collection

The geopolymer used as an adsorbent was developed by Dazogbo from Kaolinite collected with Ferdinand Goudjo in the commune of Ketou in Benin. The industrial wastewater samples were collected at CHU-MEL (University Hospital Center of Mother and Child Lagoon) located at Cotonou in Benin. The technique recommended by APHA et al. [11] was used for wastewater sampling. Using the AQUARED brand multiparametric probe, several physicochemical parameters such as Temperature, Electric Conductivity, Dissolved Oxygen, Total Dissolved Solids, Salinity, Redox potential were measured in situ.

The development of Kaolinite geopolymer followed several stages ranging from preliminary treatment (grinding, sieving of raw kaolin), decarbonation with hydrochloric acid, extraction of clay fraction, formation of metakaolin and actual formation of geopolymer (Figure 1) using the cetyltrimethyl ammonium bromide (CTAB) activation method with in an alkaline medium following the procedures reported by Dazogbo [2].

Figure 1. Clay transformation: Raw clay (A) and elaborated geopolymer (B)

2.2. Analytical Methods

Relevant chemicals were hydrochloric acid (37 %), sodium hydroxide (97%), copper sulphate pentahydrate (98%), copper reagent (CuVer 1), Paracetamol (500 mg tablet), distilled water and geopolymer powder made from Kaolinite.

To carry out the tests and analyses, we used a range of laboratory equipment, the most relevant of which are: a mini-flocculator, a pH meter/thermometer, a UV-Visible spectrophotometer (DR500), Centrifuge (80-2), colorimeter (DR890) and a multiparameter probe (AQUARED).

The working (standard) solutions, which were used, are namely: Cu²⁺(aq). 5 ppm, prepared by dissolving 39.3 mg of CuSO₄.5H₂O in 2 L of distilled water. Preliminary verification of the copper content was carried out by 4 tests and instead showed an average concentration of 4 ppm. The aqueous solution of 100 ppm of paracetamol was obtained by dissolving 200 mg of paracetamol powder in 2 L of distilled water.

Indeed, Copper dosage was carried out at the Applied Hydrology Laboratory (LHA) using the colorimetric method with the DR890 colorimeter (program 20) based on the Beer-Lambert principle as shown by eq. (1), which relates the absorbance of a solution when it is crossed by light of a specific wavelength in a well-defined path, with the concentration of the absorbing species [12]. In the same purpose, the bicinchoninate technique was used (HACH method), where the cupric ions form a complex with the violet-colored bicinchoninic acid, which absorbs at 454 nm.

Where A is the absorbance, ε denote the absorptivity constant (L.mol⁻¹.cm⁻¹), l is the optical distance (cm) and C is the concentration in mol.L⁻¹.

Furthermore, Paracetamol concentration was determined by UV-visible spectrophotometry, and the equation obtained during the calibration curve is presented in Figure 2. The DR500 UV-Visible spectrophotometer set to program 880 was used to read the absorbance.

Figure 2. Calibration curve for paracetamol solution at λ = 280 nm

By using the quantum chemistry modeling methods via VASP (Vienna Ab initio Simulation Package), the related eq. (2) was solved by specific pseudo-potentials of adsorption energy [13,14,15].

Where is the adsorption Energy and X denote Cu²⁺/Para.

The temperature effect on the molecule adsorption was determined by calculating the free energies of adsorption reactions at different temperatures in eq. (3) [16]:

With the adsorption energy, is zero-point energy, is the translation energy, is the rotational energy, denote the translational entropy and is the rotational entropy.

3. Experimental Process

During the adsorption tests, the flocculation technique was used, and the yield was calculated using eq. (4).

Where, denotes the initial concentration, is the concentration at equilibrium.

To reduce the organic charges, 100 mL of liquid sample was taken to which the optimal mass of the geopolymer was added, and the mixture was stirred for a given time. At the end of adsorption, centrifugation was carried out and finally the analysis. The mass effect was obtained by the curve, , while that of the pH was determined at the pH with maximum absorbance. The kinetics of elimination was evaluated by the curve, and the maximum absorption capacity were obtained by the remainder method at different concentrations of the wastewater sample, with eq. (5).

The isotherms were modeled by the Langmuir eq. (6) [17] and Freundlich eq. (7) [18]:

As for kinetic modelling, two most common models were used: Lagergren (Pseudo-First Order “PFO”) by eq. (8) and Blanchard (Pseudo-Second-Order “PSO”) using the eq. (9) [19,20]:

These kinetic models follow the thermodynamic equilibrium by the relation:

Which allowed deducing other kinetic parameters such as ∆G, ∆H and ∆S.

The levels of each parameter retained for optimization are shown in the following table. After defining the initial conditions for each test, batch tests were carried out to optimize the parameters, with each previously optimized parameter being used directly in the next test as described in Table 1.

Table 1. Levels retained for each parameter

Figure 3. a) Free surface of kaolinite, b) Adsorption mechanism of Copper on Kaolinite Surface

Figure 4. Adsorption mechanism of Paracetamol (vertical, Horizontal) on Kaolinite Surface

4. Results and Discussion

4.1. Adsorption by Quantum Chemistry Approach

The quantum chemistry predicted the deposition surfaces of copper in Figure 3 and paracetamol in Figure 4. It should be noted that the deposition of copper is unique and does not depend on orientation, only the forces of electrostatic attraction forces governing the deposition site of either on hydrogen (-139.00 kJ.mol⁻¹) or on oxygen (-139.15 kJ.mol⁻¹), while paracetamol could be deposited in two orientations, horizontal more favoured (-159.40 kJ.mol⁻¹) than vertical (-91.10 kJ.mol⁻¹) seen in Table 2.

Table 2. Adsorption energies and positions of Copper and Paracetamol on Kaolinite surface

The Figure 5 shows the profile of the variation of the free energy of adsorption as a function of temperature. These results therefore show that it is possible to regenerate kaolinite by heating it up to 435 K to eliminate the DR and to 780 K if it is TME. The removal of the adsorbed water during the process does not interfere in any way, since the kaolinite will always be in contact with the wastewater.

Figure 5. Evolution of adsorption energy of Copper and Paracetamol on Kaolinite surface

4.2. Adsorption by Experimental Approach

Table 3 reports the optimization procedure. It appears that all the parameters have an effect on the adsorption of TME and DR on kaolinite-geopolymer. The adsorption efficiency increases with the increase of the mass of the geopolymer as reported by several authors [21,22] and this is due to the availability of a greater number of sites on the Kaolinite surface.

Table 3. Optimal levels of the studied parameters

Previous authors reported rapid adsorption of cupric ions on clays: Choumane [22] reached the equilibrium state at 20 minutes, while the result obtained by Chouchane et al. [23] perfectly matches that of this study, 30 minutes were enable for the equilibrium to be reached between the Cu2+ ions and the raw Kaolin powder in an aqueous medium. Gusain et al. [24] observed the same results during the removal of copper by modified sand. Bakhtiari & Azizian [25] also obtain an equilibrium time of 30 minutes by eliminating copper using nanoporous Metal-Organic Framework-5 (MOF-5). In the case of paracetamol, equilibrium was reached faster on Kaolinite at 25 minutes than on the material based on bentonite, cement and coal, which took 180 minutes [26]. However, this contact time is better within the range of 20-30 minutes as it was observed by Djemai and Boukrouk [27] on the elimination of Paracetamol by ZnFe₂O₄ for a yield of 57.97%. The Kaolinite geopolymer is more effective since its yield is 63% at this time.

In this study, we note that the optimum stirring speed for copper adsorption was 200 rpm such as in Chouchane et al. [23] but different from that reported by Melle [28] for whom the optimum value was of 400 rpm.

Moreover, for pH, the results show that the alkaline medium is the best; this is explained by the surface charge on the adsorbent material. The optimal temperature for the adsorption of copper is 30°C (303 K), while that of paracetamol is 25°C (298 K), on Geopolymer by kaolinite and beyond these temperatures, the yield gradually decreases. These results were also reported by Khireddine et al. [29] during the adsorption of paranitrophenol on kaolinite intercalated with urea. Several authors have encountered this phenomenon; this is the case of Errais [30] during the adsorption of dye (Congo red) on kaolinite, as well as the adsorption of trace metals on Thai kaolin and ball clay [31]. Therefore, the optimal concentrations are 1 ppm for copper but the yields are not far from other concentrations. For paracetamol it was 80 mg/L. The Table 3 gives the optimal level for the studied parameters.

Figure 6. Profile of the distribution constant (Kd) and the Temperature

Starting from the relationship lnKd = f(1/T) obtained on Figure 6, the calculated energy values (Table 4) show that all the enthalpies and Gibbs energies are negative, which implies that the adsorption of copper and paracetamol is exothermic and spontaneous.

Table 4. Gibbs Energy, Enthalpy and Entropy (kJ.mol⁻¹) during adsorption of Copper and Paracetamol on Kaolinite surface

The free energies obtained at optimal temperatures (303 K and 298 K) are respectively -8.33 kJ.mol⁻¹ and -5.60 kJ.mol⁻¹ and deviate widely from those calculated theoretically, this could be explained by modification of the structure of kaolinite during the formation of the geopolymer, in the sense that it is heated to a high temperature and yet the DFT calculations are carried out on pure Kaolinite. However, these energies are higher than that obtained at 293 K (-1.72 kJ.mol⁻¹) by Chouchane et al. [23] in the adsorption of copper, but very close to -5.445 kJmol-1, encountered at 298 K by Meriem & Mouad [26] in the adsorption of paracetamol on the composite material of clay-cement-coal.

These values which are between 0 and 40 kJ.mol⁻¹, correspond to the physisorption type adsorption energy which is exothermic and would be linked to electrostatic interactions [24,29,30], in the sense that the paracetamol which forms weak interactions also showed a low energy as predicted theoretically for a vertical attack (-91.1 kJ.mol⁻¹) where there are fewer hydrogen bonds formed than for the horizontal attack (-159.4 kJ.mol⁻¹) giving the possibility of forming more bonds.

The fact that the Entropy values are negative and very low shows that the adsorption of paracetamol and Cu does not lead to significant molecular and structural disorder either in the adsorbate level or at the adsorbent level [32]. This makes the elaborated Geopolymer an ideal material for this elimination, which can be used several times and maintain its effectiveness.

4.3. Adsorption Capacity

4.3.1. Kinetic Modeling

The simulation of adsorption kinetics was carried out according to Lagergren's law for pseudo-first order, while that of pseudo-second order by Blanchard's law. The calculated values obtained for the rate constant, the coefficient of determination and the maximum adsorption capacity are summarized in Table 5. For both adsorbates, it turns out that the Blanchard model better represents the adsorption mechanism on kaolinite. The coefficients of determination for the regressions are closed to 1 (R² > 0.99). The calculated values by the kinetic modelling equations show a maximum adsorption capacity per gram of kaolinite of 5.207 mg of copper for a solution concentration of 4 mg/L, and 116.302 mg in that of paracetamol for a concentration of 80 mg/L, which are very close to the Qe values obtained experimentally, i.e., 5.165 and 114.70 mg/g respectively, which confirms that pseudo-second order kinetics better describes this phenomenon.

Table 5. Kinetic parameters of Pseudo-first order and Pseudo-second order adsorption models of Copper (4 ppm) and Paracetamol (80 ppm)

The simulation of the kinetic adsorption models shows that the pseudo-second order model is totally similar with the experimental model (Figure 7), which shows that the latter better simulates this adsorption, and this corroborates with the observation according to their R² value according to which that of copper was greater than that of Paracetamol.

4.3.2. Isotherm Modeling

The isotherms were drawn for the parameterized tests in the same way as the kinetic study. By plotting the adsorption capacity as a function of residual concentration at equilibrium (Qe = f(Ce)), the plot gave the isotherms presented in Figure 8. Based on their appearance, that of copper is of the “C” type isotherm, while that of Paracetamol is of the “S” type according to the classification of Giles et al. [33]. However, according to Brunauer [34], the adsorption isotherm of copper is of type III and that of Paracetamol in type V.

The modelling of the isotherm was carried out according to the Langmuir and Freundlich models described by the equations, at different concentrations. The results obtained are presented in Table 6. Based on these isotherms, the adsorption of copper on the Kaolinite-based geopolymer is well represented by the two models; their determination indices are greater than 0.99, that of Langmuir (R² = 0.997) slightly outweighs that of Freundlich (R² = 0.993).

The same observation is valid during the adsorption of paracetamol, although the coefficients are low (R² < 0.95) and that of Langmuir is larger than that of Freundlich. The adsorption capacities calculated by the Langmuir equation are: 25.97 mg/g for copper and 181.82 mg/g for paracetamol. The adsorption speed of copper is faster than that of paracetamol as illustrated by their Langmuir constants.

The simulation of the isotherms according to the Langmuir and Freundlich equations produced isotherm profiles are presented in Figure 9. The simulated Langmuir model is completely similar with that of Freundlich; this is explained by their coefficients of determination, which are very close for the linearized equations. However, for the two substances, the experimental isotherm is well matched to the others in low concentrations only and the non-alignment is very pronounced in the adsorption of paracetamol.

Figure 7. Simulation of kinetic models of adsorption of Copper and Paracetamol on Kaolinite Surface

Figure 8. Adsorption isotherms of Copper and Paracetamol on Kaolinite Surface

Table 6. Parameters of the Langmuir and Freundlich models of Copper and Paracetamol adsorbed on Kaolinite Surface

Figure 9. Adsorption isotherms simulation of Copper and Paracetamol on Kaolinite Surface

Figure 10. Variation in the concentration of Copper and Paracetamol compared to the discharge standard before and after treatment with Kaolinite (Cav: Concentration before treatment, Cap: Concentration after treatment, FS: Septic tank, ES: WWT entry, SS: WWT exit)

4.4. Application to Wastewater Treatment

The copper and paracetamol concentrations in the wastewater were determined before (Cav) and after (Cap) treatments. The obtained values made possible the calculation of the adsorption efficiencies. From the results, we noted that only the ES site before treatment has a copper concentration higher than the Beninese standard for discharge into the receiving environment. This concentration is 2.93 mg/L lower than that encountered by Todedji et al. [35] in wastewater at the entrance to the CHU-MEL WWTP. The treatment of hospital wastewater gave an average yield of 90.5 ± 2.10%, which shows that this Kaolinite process is very effective for the elimination of copper in wastewater. The concentrations found after treatment vary from 0.013 to 0.034 mg/L. In the elimination of paracetamol, the process gave an average yield of 88.5 ± 3.65%.

Table 7. Reduction rates of the concentration of copper and paracetamol after treatment with kaolinite (FS: Septic tank, ES: WWT entry, SS: WWT exit)

5. Conclusion

The aim of this study to assess and optimize the adsorption method of cooper ions and paracetamol on kaolinite adsorbent industrial wastewater treatment purpose. The study started with a quantum chemical investigation for the prediction of the adsorption mechanism. The second step consisted of batch test experiments in aqueous solutions of copper and paracetamol and the last one was the application of the optimized method to industrial wastewater collected. The results brought us to the following conclusions: the alkaline activation Kaolinite under the CTAB showed a reduction rate in the copper concentration of 90.3% and 71.7% in the aqueous standard solutions for Cu²⁺ (4 mg. L⁻¹) and paracetamol (80 mg/L). For hospital wastewater, the study revealed elimination rates of 90.5 ± 2.10% and 88.5 ± 3.65% from the respective contents of copper and paracetamol.

This investigation contributed to the improvement of a procedure for using the adsorbent potential of Ketou kaolinite clay, and may be profitable in the treatment of industrial wastewater to combat aquatic-ecosystem health degradation due to pollution by emerging micro-pollutants. It is noted that only the behaviours of Copper and Paracetamol on the geopolymer have been studied and their representativeness in the respective chemical classes remains insignificant. Therefore, the extension of this study to other micro-pollutants is a necessary and useful prospect.

ACKNOWLEDGMENTS

We are grateful to the African Centre of Excellence for Water and Sanitation (C2EA), for granting us on same fieldworks, and to URSTIME-ISP/Bukavu, which paid part of the Laboratory of Chemical Physics-Materials and Molecular Modeling (LCP3M) in Benin and though the K-CTN (ARES-PRD) project.

References

[1]   | Laibi, A.B., Gomina, M., Sorgho, B., Sagbo, E., Blanchart, P., Boutouil, M., Sohounhloule, D.K.C. Caractérisation physico-chimique et géotechnique de deux sites argileux du Bénin en vue de leur valorisation dans l’éco-construction. Int. J. Biol. Chem. Sci., 11(1), 2017, 499–514.
[2]   | Dazogbo, P.G. “Elaboration de géopolymères à base d’argile locale pour la dépollution des eaux usées industrielles,” Master Thesis, University of Abomey-Calavi, Bénin, 2022.
[3]   | Sawadogo, B., “Traitement des eaux usées industrielles par des procédés membranaires sous climat sahélien : cas des eaux usées de brasserie au Burkina Faso,” PhD Thesis, University of Montpellier, France, 2018.
[4]   | Elegbede, M.B., Sohounnon, M., Dovonou, F., Koumolou, L., Edorh, P.A. “Évaluation des risques d’intoxication alimentaire liés à la consommation des produits halieutiques du lac Nokoué, Bénin, Afrique de l’Ouest,” 2020.
[5]   | Yehouenou, A.P.E., Fayomi, B., Azocli, D., Acakpo, H., Soton, A., Boko, M., Fourn, L., Houinsa, D., Kèkè, J-C., Qualité des eaux d’arrosage utilisées sur le site maraîcher de Houéyiho de Cotonou au Sud-Bénin, Bulletin de la Recherche Agronomique du Bénin, TropicAgrif. 65, 2009, 32–37.
[6]   | Yessoufou, A., Daouda, M., Fidèle, S., Eric, A.B., Fayomi, C.D., Comlan, A.D., Pharmaceuticals and Personal Care Products (PPSPS) in the Aquatic Environment: Status and Issues in the Republic of Benin, Research Journal of Pharmaceutical Sciences, 5(3), 2016, 1–15.
[7]   | Gross-Sorokin, M.Y., Roast, S.D., Brighty, G.C., Assessment of Feminization of Male Fish in English Rivers by the Environment Agency of England and Wales. Environmental Health Perspectives, 114(S-1), 2005, 147–151.
[8]   | Poiger, T., Buser, H-R., Müller, M.D., Photodegradation of the pharmaceutical drug diclofenac in a lake: Pathway, field measurements, and mathematical modeling. Environ. Toxicol. Chem., 20(2), 2001, 256–263.
[9]   | Lasagna, M., Mancini, S., De Luca, D.A., Aquifer protection from overexploitation: Example of actions and mitigation activities used in the Maggiore Valley (Asti Province, NW Italy), GEOINGEGNERIA AMBIENTALE E MINERARIA, 156, 2019, 30–38.
[10]   | Gbaguidi, J.G, Topanou, N., Fatombi, J., Akpo, E., Mama, D., Aminou, T., Contributions to the protection of a lentic system in the tropical region against chemical pollutions: A case study of ‘Toho Lake’ in Southeastern Benin, West Africa, Journal of Bioscience and Applied Research, 6, 2020, 8–19.
[11]   | Apha, Awwa, Wef, Standard Methods for examination of water and wastewater. 22nd Edition. American Public Health Association, WashingtonDC. 2012.
[12]   | Skoog, D.A., West, D.M., Holler, F.J., Crouch, S.R., Buess-Herman, C., Chimie analytique, 3rd ed. Paris: de Boeck, 2014.
[13]   | Hounfodji, J.W., Kanhounnon, W.G., Kpotin, G., Atohoun, G.S., Lainé, J., Foucaud, Y., Badawi, M., Molecular insights on the adsorption of some pharmaceutical residues from wastewater on kaolinite surfaces. Chemical Engineering Journal, 2020, 127176.
[14]   | Merrouche, N., Lahmar, A.F., Étude théorique et expérimentale des kaolins (Étude par DFT), Master Thesis, University of ABDERAHMANE MIRA-BEJAIA, Algérie, 2015.
[15]   | Badawi, M., Cristol, S., Paul, J.F., Payen, E., “DFT study of furan adsorption over stable molybdenum sulfide catalyst under HDO conditions,” Comptes Rendus Chimie, 12, 2009, 6–7.
[16]   | Jenkins, S.A., Waszkiewicz, S., Quarini, G.L., Tierney, M.J., Drying saturated zeolite pellets to assess fluidised bed performance. Applied Thermal Engineering, 22(7), 2002, 861–871.
[17]   | Sun, X., Yang, Q., Meng, R., Tan, C., Liang, Q., Jiang, J., Ye, H., Chen, X., Adsorption of gas molecules on graphene-like InN monolayer: A first-principle study. Applied Surface Science, 404, 2017, 291–299.
[18]   | H. Freundlich, “Über die Adsorption in Lösungen,” Zeitschrift für Physikalische Chemie, 57U (1), 1907, 385–470.
[19]   | B. Sorgho, B. Guel, L. Zerbo, M. Gomina, and P. Blanchart, “A study of adsorption of cadmium, copper and lead by two clays from Burkina Faso,” Int. J. Biol. Chem. Sci., 12(6), 2019, 2933.
[20]   | Kayode, A.D., Sunday, A.S., Oluyemi, A.S., Abidemi, I.O., Folasade, A.A., Gbolahan, A.M., Kayode, P.O., Ionic surfactant enhancement of clay properties for heavy metals adsorption: Kinetics and isotherms, Indonesian Journal of Chemistry, 21(4), 2021, 825–841.
[21]   | Abdelkader, D., Abdelmalek, B., Sidi Mohammed, A.M., Identification et prévision du gonflement de quelques sols de la région de Tlemcen (Algérie), Bulletin Des Laboratoires Des Ponts Et Chaussées, 233, 4375, 2001, 67–75.
[22]   | Choumane, F.Z., Elimination des métaux lourds et pesticides en solution aqueuse par des matrices argileuses, Thèse de Doctorat, Université Abou Bekr Belkaid-Tlemcen, Algérie, 2015.
[23]   | Chouchane, T., Yahi, M., Boukari, A., Balaska, A., Chouchane, S., Adsorption du cuivre en solution par le kaolin Adsorption of the copper in solution by the kaolin, J. Mater. Environ. Sci, 7(8), 2016, 2825–2842.
[24]   | Gusain, D., Srivastava, V., Sharma, Y.C., Kinetic and thermodynamic studies on the removal of Cu(II) ions from aqueous solutions by adsorption on modified sand, Journal of Industrial and Engineering Chemistry, 20(3), 2014, 841–847.
[25]   | Bakhtiari, N., Azizian, S., Adsorption of copper ion from aqueous solution by nanoporous MOF-5: A kinetic and equilibrium study, J Mol Liq, 206, 2015, 114–118.
[26]   | Meriem, B., Mouad, B., Elimination des médicaments (paracétamol) sur un composite de confinement, Master thesis, Ecole Nationale Polytechnique, Algérie, 2017.
[27]   | Djemai, C., Boukrouk, A., Contribution à l’étude de l’élimination de Polluants Émergents de type Pharmaceutiques par Adsorption,” mémoire de master, Université Mohammed Seddik Benyahia – Jijel, Algérie, 2020.
[28]   | Melle, T.K., Elimination des Métaux lourds en solution aqueuse par les argiles Algériennes, Master Thesis, University of Abou Bekr Belkaid-tlemcen, Algérie, 2013.
[29]   | Khireddine, O., Berredjem, Y., Hailaimia, F., Nouacer, S., Djellaibi, R., Bensid, N., Boulmokh, A., Removal of Para -Nitrophenol by Adsorption on Intercalated Natural Clay, Sens Lett, 14(3), 2018, 258–265.
[30]   | Errais, E., Réactivité de surface d’argiles naturelles : Etude de l’adsorption de colorants anioniques, PhD Thesis, UNIVERSITY OF STRASBOURG, 2011.
[31]   | Chantawong, V., Harvey, N.W., Bashkin, V.N., Comparison of heavy metal adsorptions by Thai kaolin and ballclay, Water Air Soil Pollut, 148, 2003, 1–4.
[32]   | Malima, N.M., Owonubi, S.J., Lugwisha, E.H., Mwakaboko, A.S., Thermodynamic, isothermal and kinetic studies of heavy metals adsorption by chemically modified Tanzanian Malangali kaolin clay, International Journal of Environmental Science and Technology, 18(10), 2021, 3153–3168.
[33]   | Giles, C.H., Smith, D., Huitson, A., A general treatment and classification of the solute adsorption isotherm. I. Theoretical, J Colloid Interface Sci, 47(3), 1974, 755–765.
[34]   | Sing, K.S.W., Pioneers of Adsorption Science 1. Stephen Brunauer. Adsorption Science & Technology, 32(5), 2014, 343–350.
[35]   | Todedji, J., Somadje O.J., W., Chouti, K.C., Degbey, C., Dedjiho, A., Mama, D., Evaluation de l’efficacité du traitement chimique des effluents hospitaliers universitaires du département du littoral en République du Bénin, J. Soc. Ouest-Afr. Chim, 50, 2021, 30–40.