@article{jfnr2021964,
author={{Lin, Yung-Kai and Kao, Yu-Yu and Liu, Cheng and Liang, Chia-Hua and Lin, Yung-Hsiang and Hu, Wei-Chun and Chiang, Chi-Fu},
title={Effects of a Fermented Grape Combined with Specified Fruits and Vegetables or Their Extracts on Anti-aging and Anti-inflammatory Status: A Randomized Controlled Clinical Trial},
journal={Journal of Food and Nutrition Research},
volume={9},
number={6},
pages={292--296},
year={2021},
url={http://pubs.sciepub.com/jfnr/9/6/4},
issn={2333-1240},
abstract={Vegetables and fruits had antioxidant capacity. Fermented grapes had a higher content of anthocyanins and flavonoids, and reduced skin wrinkles. There were not more clinical studies on whether fermented grapes with fruit and vegetable extracts had anti-aging and anti-inflammatory activities. The current study used fermented grapes beverages made from fermented grapes combined with fruit and vegetable extracts to explore anti-aging and anti-inflammatory. 60 subjects were recruited and divided into a placebo and another fermented grape drinks group. The subjects drank 50 ml , 1 bottle a day for 8 week. After drinking for 8 weeks, a skin test and blood inflammatory factor analysis were performed. Compared to the placebo group, skin brightness, moisture, elasticity was significantly increased by 3.6%, 4.9%, 5.4%, respectively. Fermented grape drinks decreased skin spots, and wrinkles by 7.0%, and 19.0%, respectively. TNF-¦Á (Tumor Necrosis Factor) and IL-6 (Interleukin-6) expression were decreased, also, as a function of fermented grape drinks intakes. This study indicated that fermented grapes combined with fruit and vegetable extracts can significantly improve the brightness, moisture, elasticity, wrinkles, pores, and decrease TNF-¦Á and IL-6 expression.},
doi={10.12691/jfnr-9-6-4}
publisher={Science and Education Publishing}
}