@article{jfnr2021923,
author={{Lin, Yung-Kai and Hu, Wei-Chun and Chiang, Chi-Fu},
title={Antioxidant Capacity and Immune Regulation Properties of a Herbal Mixture Including <i>Sparassis crispa</i>, <i>Aureobasidium pullulan</i>, and <i>Ganoderma lucidum</i>},
journal={Journal of Food and Nutrition Research},
volume={9},
number={2},
pages={73--78},
year={2021},
url={http://pubs.sciepub.com/jfnr/9/2/3},
issn={2333-1240},
abstract={Many Chinese herbal medicines have been proven to have anti-inflammatory effects. Among them, edible and medicinal mushrooms are rich in a variety of physiologically active ingredients, which can enhance immunity and are good materials for the development of health foods. This article aims to investigate the beneficial effects of SOD Light, a herbal formula consisting of <i>Sparassis </i><i>c</i><i>rispa</i>, <i>Aureobasidium pullulan</i>, and <i>Ganoderma lucidum</i>, on anti-inflammation, antioxidant, and immune-modulation. SOD Light was able to inhibit ROS expression level and boost the SOD activity in PBMCs by 11% and 43.8%, respectively, as compared with the control group, and the significant improvement effect of the phagocytic activity of neutrophils was exhibited. Moreover, SOD Light also significantly enhanced the expression of the lymphocyte development-associated and adaptive immune-related genes (i.e., <i>CD134</i>, <i>CD26</i>, <i>CD96</i>, <i>CD247</i>, and <i>IL-16</i>). This study successfully unveils that the combination of <i>S</i><i>.</i><i> </i><i>c</i><i>rispa</i>, <i>A</i><i>.</i><i> pullulans</i>, and <i>G</i><i>.</i><i> lucidum</i> was available for anti-oxidation, cytokines production, enhancement of T cell activation, and lymphocyte development in PBMCs, which implies that SOD Light are beneficial for immune modulation.},
doi={10.12691/jfnr-9-2-3}
publisher={Science and Education Publishing}
}