eng Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 2020-07-12 8 6 268 272 10.12691/jfnr-8-6-4 JFNR2020864 article Hui-Chun Chang 1 Chia-Hua Liang 2 Yen-Ju Lin 3 Yung-Hao Lin 3 Yung-Hsiang Lin 3 Chen-Meng Kuan Chenmeng.Kuan@tci-bio.com 3 Research & Design Center, TCI CO., Ltd., Taipei, Taiwan Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan Research & Design Center, TCI Gene Inc., Taipei 114, Taiwan This preliminary clinical study demonstrates the possibility of a prebiotic juice for improvement of skin conditions. Recently, the health benefits of probiotics and prebiotics for prevention/treatment of diseases have been underscored in the medical field. However, it is challenging to uphold the viability of probiotics in drinks with low pH ranges (e.g., juices), while prebiotics are possible to overcome the impediment. In this study, we utilized a berry juice with xylooligosaccharides (XOS) to explore the clinical benefits for skin heath. There is little clinical evidence for the XOS applications in anti-aging. After 8-week juice-XOS intervention, in comparison with the baseline results, the mean levels of skin brightness, moisture, elasticity, spots, UV spots, and brown spots of subjects were improved by 2.7%, 11%, 5.1%, 3.1%, 6.2%, and 0.6%, respectively. Besides UV spots, the results of other skin parameters at 8 weeks in juice-XOS group were significantly different from the baseline results. Nevertheless, juice-XOS did not exert an obvious improving effect on body composition since the XOS content was too few to impart a remarkable improving effect on metabolism as evidenced by the previous reports. In brief, we demonstrated that prebiotic juice may provide an alternative route to daily skincare although the underlying mechanism of juice-XOS for improvement of skin health is not clear. http://pubs.sciepub.com/jfnr/8/6/4/jfnr-8-6-4.pdf xylooligosaccharides berry juice skin aging anti-aging