eng Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 2020-11-27 8 11 670 674 10.12691/jfnr-8-11-7 JFNR20208117 article Jos¨¦ Octavio Rodiles-L¨®pez 1 Marcela Gonz¨¢lez-Montoya hector.martinez.flores@umich.mx 1 H¨¦ctor Eduardo Mart¨ªnez-Flores 1 Rafael Zamora-Vega 1 Facultad de Qu¨ªmico Farmacobiolog¨ªa. Tzintzuntzan 173. Col. Matamoros. C.P. 58240. Universidad Michoacana de San Nicol¨¢s de Hidalgo. Morelia, M¨¦xico Avocados are characterized by their high dietary fiber and unsaturated fatty acids content. This study aimed to evaluate the hypolipidemic and hypocholesterolemic effect of avocado Hass on hamsters fed with diets based on freeze-dried pulp avocado (FAD) and defatted paste avocado (DPAD). Total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), serum triglycerides (TG), and atherogenic index of plasma (AIP) were evaluated along with total lipids in liver and feces. Compared to the control diet, FAD and DPAD reduced the serum TG levels by 76.47 and 46.06%, respectively. FAD also reduced the serum TC levels by 16.39%. FAD and DPAD decreased the lipids in the liver by 33.61% and 10.0% and the amount of lipid excreted in feces by 73.47% and 41.50%, respectively. FAD showed the lowest AIP, 0.60, compared to that of DPAD and the control, 1.83 and 1.94, respectively. Freeze-dried avocado pulp was found to be efficient in reducing dyslipidemia values in hamsters. http://pubs.sciepub.com/jfnr/8/11/7/jfnr-8-11-7.pdf avocado freeze-drying hamsters triglycerides cholesterol